Protolysis and Complex Formation of Organophosphorus Compounds—Characterization by NMR-Controlled Titrations

Phosphonic acids, aminophosphonic acids, and phosphonocarboxylic acids are characterized by an advanced hyphenated technique, combining potentiometric titration with NMR spectroscopy. Automated measurements involving (13)C, (19)F and (31)P nuclei lead to “pseudo 2D NMR” spectra, where chemical shift...

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Detalles Bibliográficos
Autor principal: Hägele, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766815/
https://www.ncbi.nlm.nih.gov/pubmed/31492010
http://dx.doi.org/10.3390/molecules24183238
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author Hägele, Gerhard
author_facet Hägele, Gerhard
author_sort Hägele, Gerhard
collection PubMed
description Phosphonic acids, aminophosphonic acids, and phosphonocarboxylic acids are characterized by an advanced hyphenated technique, combining potentiometric titration with NMR spectroscopy. Automated measurements involving (13)C, (19)F and (31)P nuclei lead to “pseudo 2D NMR” spectra, where chemical shifts or coupling constants are correlated with analytical parameters. Dissociation constants, stability constants, dynamic and specific chemical shifts are determined. Macroscopic and microscopic dissociation equilibria are discussed.
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spelling pubmed-67668152019-10-02 Protolysis and Complex Formation of Organophosphorus Compounds—Characterization by NMR-Controlled Titrations Hägele, Gerhard Molecules Perspective Phosphonic acids, aminophosphonic acids, and phosphonocarboxylic acids are characterized by an advanced hyphenated technique, combining potentiometric titration with NMR spectroscopy. Automated measurements involving (13)C, (19)F and (31)P nuclei lead to “pseudo 2D NMR” spectra, where chemical shifts or coupling constants are correlated with analytical parameters. Dissociation constants, stability constants, dynamic and specific chemical shifts are determined. Macroscopic and microscopic dissociation equilibria are discussed. MDPI 2019-09-05 /pmc/articles/PMC6766815/ /pubmed/31492010 http://dx.doi.org/10.3390/molecules24183238 Text en © 2019 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Perspective
Hägele, Gerhard
Protolysis and Complex Formation of Organophosphorus Compounds—Characterization by NMR-Controlled Titrations
title Protolysis and Complex Formation of Organophosphorus Compounds—Characterization by NMR-Controlled Titrations
title_full Protolysis and Complex Formation of Organophosphorus Compounds—Characterization by NMR-Controlled Titrations
title_fullStr Protolysis and Complex Formation of Organophosphorus Compounds—Characterization by NMR-Controlled Titrations
title_full_unstemmed Protolysis and Complex Formation of Organophosphorus Compounds—Characterization by NMR-Controlled Titrations
title_short Protolysis and Complex Formation of Organophosphorus Compounds—Characterization by NMR-Controlled Titrations
title_sort protolysis and complex formation of organophosphorus compounds—characterization by nmr-controlled titrations
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766815/
https://www.ncbi.nlm.nih.gov/pubmed/31492010
http://dx.doi.org/10.3390/molecules24183238
work_keys_str_mv AT hagelegerhard protolysisandcomplexformationoforganophosphoruscompoundscharacterizationbynmrcontrolledtitrations

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