Geriatric assessment and 1‐year mortality in older patients with cancer in the head and neck region: A cohort study

BACKGROUND: The aim is to describe the association of functional capacity and cognitive functioning with 1‐year mortality in older patients with cancer in the head and neck region. METHODS: We performed a cohort study in which all patients aged 70 years and older received a geriatric screening befor...

Descripción completa

Detalles Bibliográficos
Autores principales: van Deudekom, Floor J., van der Velden, Lilly‐Ann, Zijl, Willianne H., Schimberg, Anouk S., Langeveld, Anton P., Slingerland, Marije, Blauw, Gerard J., Mooijaart, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766841/
https://www.ncbi.nlm.nih.gov/pubmed/30816619
http://dx.doi.org/10.1002/hed.25714
Descripción
Sumario:BACKGROUND: The aim is to describe the association of functional capacity and cognitive functioning with 1‐year mortality in older patients with cancer in the head and neck region. METHODS: We performed a cohort study in which all patients aged 70 years and older received a geriatric screening before treatment. Main outcome was 1‐year mortality. RESULTS: A total of 102 patients were included. Median age was 78.7 years (interquartile range [IQR], 72.3‐84.5), 25% were cognitive impaired, 40% were malnourished, and 28.4% used a walking device. Overall, 1‐year mortality was 42.3%. Male sex (hazard ratio [HR], 4.30; 95% confidence interval [CI], 1.35‐13.67), malnutrition (HR, 2.55; 95% CI, 1.19‐5.16), and using a walking device (HR, 2.80; 95% CI 1.13‐6.93) were associated with higher mortality risk, independent of stage and comorbidities. CONCLUSION: In older patients with head and neck cancer, the mortality rates are high. Nutritional status and mobility are determinants of 1‐year mortality, independent of tumor stage, age, and comorbidity.

Ejemplares similares