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Geriatric assessment and 1‐year mortality in older patients with cancer in the head and neck region: A cohort study

BACKGROUND: The aim is to describe the association of functional capacity and cognitive functioning with 1‐year mortality in older patients with cancer in the head and neck region. METHODS: We performed a cohort study in which all patients aged 70 years and older received a geriatric screening befor...

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Autores principales: van Deudekom, Floor J., van der Velden, Lilly‐Ann, Zijl, Willianne H., Schimberg, Anouk S., Langeveld, Anton P., Slingerland, Marije, Blauw, Gerard J., Mooijaart, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766841/
https://www.ncbi.nlm.nih.gov/pubmed/30816619
http://dx.doi.org/10.1002/hed.25714
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author van Deudekom, Floor J.
van der Velden, Lilly‐Ann
Zijl, Willianne H.
Schimberg, Anouk S.
Langeveld, Anton P.
Slingerland, Marije
Blauw, Gerard J.
Mooijaart, Simon P.
author_facet van Deudekom, Floor J.
van der Velden, Lilly‐Ann
Zijl, Willianne H.
Schimberg, Anouk S.
Langeveld, Anton P.
Slingerland, Marije
Blauw, Gerard J.
Mooijaart, Simon P.
author_sort van Deudekom, Floor J.
collection PubMed
description BACKGROUND: The aim is to describe the association of functional capacity and cognitive functioning with 1‐year mortality in older patients with cancer in the head and neck region. METHODS: We performed a cohort study in which all patients aged 70 years and older received a geriatric screening before treatment. Main outcome was 1‐year mortality. RESULTS: A total of 102 patients were included. Median age was 78.7 years (interquartile range [IQR], 72.3‐84.5), 25% were cognitive impaired, 40% were malnourished, and 28.4% used a walking device. Overall, 1‐year mortality was 42.3%. Male sex (hazard ratio [HR], 4.30; 95% confidence interval [CI], 1.35‐13.67), malnutrition (HR, 2.55; 95% CI, 1.19‐5.16), and using a walking device (HR, 2.80; 95% CI 1.13‐6.93) were associated with higher mortality risk, independent of stage and comorbidities. CONCLUSION: In older patients with head and neck cancer, the mortality rates are high. Nutritional status and mobility are determinants of 1‐year mortality, independent of tumor stage, age, and comorbidity.
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spelling pubmed-67668412019-10-01 Geriatric assessment and 1‐year mortality in older patients with cancer in the head and neck region: A cohort study van Deudekom, Floor J. van der Velden, Lilly‐Ann Zijl, Willianne H. Schimberg, Anouk S. Langeveld, Anton P. Slingerland, Marije Blauw, Gerard J. Mooijaart, Simon P. Head Neck Original Articles BACKGROUND: The aim is to describe the association of functional capacity and cognitive functioning with 1‐year mortality in older patients with cancer in the head and neck region. METHODS: We performed a cohort study in which all patients aged 70 years and older received a geriatric screening before treatment. Main outcome was 1‐year mortality. RESULTS: A total of 102 patients were included. Median age was 78.7 years (interquartile range [IQR], 72.3‐84.5), 25% were cognitive impaired, 40% were malnourished, and 28.4% used a walking device. Overall, 1‐year mortality was 42.3%. Male sex (hazard ratio [HR], 4.30; 95% confidence interval [CI], 1.35‐13.67), malnutrition (HR, 2.55; 95% CI, 1.19‐5.16), and using a walking device (HR, 2.80; 95% CI 1.13‐6.93) were associated with higher mortality risk, independent of stage and comorbidities. CONCLUSION: In older patients with head and neck cancer, the mortality rates are high. Nutritional status and mobility are determinants of 1‐year mortality, independent of tumor stage, age, and comorbidity. John Wiley & Sons, Inc. 2019-02-28 2019-08 /pmc/articles/PMC6766841/ /pubmed/30816619 http://dx.doi.org/10.1002/hed.25714 Text en © 2019 The Authors. Head & Neck published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
van Deudekom, Floor J.
van der Velden, Lilly‐Ann
Zijl, Willianne H.
Schimberg, Anouk S.
Langeveld, Anton P.
Slingerland, Marije
Blauw, Gerard J.
Mooijaart, Simon P.
Geriatric assessment and 1‐year mortality in older patients with cancer in the head and neck region: A cohort study
title Geriatric assessment and 1‐year mortality in older patients with cancer in the head and neck region: A cohort study
title_full Geriatric assessment and 1‐year mortality in older patients with cancer in the head and neck region: A cohort study
title_fullStr Geriatric assessment and 1‐year mortality in older patients with cancer in the head and neck region: A cohort study
title_full_unstemmed Geriatric assessment and 1‐year mortality in older patients with cancer in the head and neck region: A cohort study
title_short Geriatric assessment and 1‐year mortality in older patients with cancer in the head and neck region: A cohort study
title_sort geriatric assessment and 1‐year mortality in older patients with cancer in the head and neck region: a cohort study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766841/
https://www.ncbi.nlm.nih.gov/pubmed/30816619
http://dx.doi.org/10.1002/hed.25714
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