Cargando…

Meiotic gene activation in somatic and germ cell tumours

BACKGROUND: Germ cell tumours are uniquely associated with the gametogenic tissues of males and females. A feature of these cancers is that they can express genes that are normally tightly restricted to meiotic cells. This aberrant gene expression has been used as an indicator that these cancer cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feichtinger, J., McFarlane, R. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Opinion Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766858/ https://www.ncbi.nlm.nih.gov/pubmed/31102330 http://dx.doi.org/10.1111/andr.12628

Ejemplares similares

Cancer germline gene activation: Friend or foe?
por: McFarlane, Ramsay J, et al.
Publicado: (2014)

Somatic mutations of KIT in familial testicular germ cell tumours
por: Rapley, E A, et al.
Publicado: (2004)

Human somatic cells subjected to genetic induction with six germ line-related factors display meiotic germ cell-like features
por: Medrano, Jose V., et al.
Publicado: (2016)

Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis
por: Planells-Palop, Vicente, et al.
Publicado: (2017)

Identification of germ cell-specific genes in mammalian meiotic prophase
por: Li, Yunfei, et al.
Publicado: (2013)

Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes
por: Feichtinger, Julia, et al.
Publicado: (2012)

Clinical Considerations for the Integration of Adjuvant Olaparib into Practice for Early Breast Cancer: A Canadian Perspective
por: Henning, Jan-Willem, et al.
Publicado: (2023)

Meta-analysis of expression of l(3)mbt tumor-associated germline genes supports the model that a soma-to-germline transition is a hallmark of human cancers
por: Feichtinger, Julia, et al.
Publicado: (2014)

How does the promoter of an oocyte-specific gene function in male germ cells?
por: MIKI, Yuka, et al.
Publicado: (2018)

Preventing the transmission of pathogenic mitochondrial DNA mutations: can we achieve long-term benefits from germ-line gene transfer?
por: Samuels, David C., et al.
Publicado: (2013)

Why do plants need the ZMM crossover pathway? A snapshot of meiotic recombination from the perspective of interhomolog polymorphism
por: Ziolkowski, Piotr A.
Publicado: (2022)

Paradoxical Behavior of Oncogenes Undermines the Somatic Mutation Theory
por: Monti, Noemi, et al.
Publicado: (2022)

Fancm has dual roles in the limiting of meiotic crossovers and germ cell maintenance in mammals
por: Tsui, Vanessa, et al.
Publicado: (2023)

ADAD2 regulates heterochromatin in meiotic and post-meiotic male germ cells via translation of MDC1
por: Chukrallah, Lauren G., et al.
Publicado: (2022)

Role of β-Catenin in Post-Meiotic Male Germ Cell Differentiation
por: Chang, Yao-Fu, et al.
Publicado: (2011)

GERM CELL TUMOURS
Publicado: (1984)

GERM CELL TUMOURS
Publicado: (1982)

CancerEST: a web-based tool for automatic meta-analysis of public EST data
por: Feichtinger, Julia, et al.
Publicado: (2014)

CancerMA: a web-based tool for automatic meta-analysis of public cancer microarray data
por: Feichtinger, Julia, et al.
Publicado: (2012)

Meiotic dysfunction accelerates somatic aging in Caenorhabditis elegans
por: Loose, Julia A., et al.
Publicado: (2022)

Expression of Arf Tumor Suppressor in Spermatogonia Facilitates Meiotic Progression in Male Germ Cells
por: Churchman, Michelle L., et al.
Publicado: (2011)

PNLDC1, mouse pre‐piRNA Trimmer, is required for meiotic and post‐meiotic male germ cell development
por: Nishimura, Toru, et al.
Publicado: (2018)

Microgravity Promotes Differentiation and Meiotic Entry of Postnatal Mouse Male Germ Cells
por: Pellegrini, Manuela, et al.
Publicado: (2010)

Synaptonemal Complex Components Promote Centromere Pairing in Pre-meiotic Germ Cells
por: Christophorou, Nicolas, et al.
Publicado: (2013)

Germ cell tumour chemotherapy.
por: Horwich, A.
Publicado: (1989)

Functional somatic disorders: discussion paper for a new common classification for research and clinical use
por: Burton, Christopher, et al.
Publicado: (2020)

Imaging of testicular germ cell tumours
por: Dalal, P U, et al.
Publicado: (2006)

DNA crosslink repair safeguards genomic stability during pre-meiotic germ cell development
por: Hill, Ross J, et al.
Publicado: (2019)

IGF signalling in germ cells and testicular germ cell tumours: roles and therapeutic approaches
por: Selfe, J., et al.
Publicado: (2019)

Understanding p53 tumour suppressor network
por: Panatta, Emanuele, et al.
Publicado: (2021)

Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells
por: Zhang, Xiaoyu, et al.
Publicado: (2023)

Somatic transposition and meiotically driven elimination of an active helitron family in Pleurotus ostreatus
por: Borgognone, Alessandra, et al.
Publicado: (2017)

Differences in polyadenylation site choice between somatic and male germ cells
por: McMahon, K Wyatt, et al.
Publicado: (2006)

Risk of testicular germ-cell tumours in relation to childhood physical activity
por: Cook, M B, et al.
Publicado: (2008)

A Germ Cell-specific Gene, Prmt5, Works in Somatic Cell Reprogramming
por: Nagamatsu, Go, et al.
Publicado: (2011)

A novel cohort of cancer-testis biomarker genes revealed through meta-analysis of clinical data sets
por: Sammut, Stephen J., et al.
Publicado: (2014)

Glycolipids of human primary testicular germ cell tumours.
por: Olie, R. A., et al.
Publicado: (1996)

Salvage therapy of germ cell tumours.
por: Horwich, A.
Publicado: (1995)

Expression and epigenomic landscape of the sex chromosomes in mouse post-meiotic male germ cells
por: Moretti, Charlotte, et al.
Publicado: (2016)

Conversion of Germ Cells to Somatic Cell Types in C. elegans
por: ul Fatima, Nida, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_o2b6umqr0ppcgd56p0ii3cu24j