Cargando…

Design and Development of Photonic Biosensors for Swine Viral Diseases Detection

In this paper we introduce a field diagnostic device based on the combination of advanced bio-sensing and photonics technologies, to tackle emerging and endemic viruses causing swine epidemics, and consequently significant economic damage in farms. The device is based on the use of microring resonat...

Descripción completa

Detalles Bibliográficos
Autores principales: Griol, Amadeu, Peransi, Sergio, Rodrigo, Manuel, Hurtado, Juan, Bellieres, Laurent, Ivanova, Teodora, Zurita, David, Sánchez, Carles, Recuero, Sara, Hernández, Alejandro, Simón, Santiago, Balka, Gyula, Bossis, Ioannis, Capo, Alessandro, Camarca, Alessandra, D’Auria, Sabato, Varriale, Antonio, Giusti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766991/
https://www.ncbi.nlm.nih.gov/pubmed/31540156
http://dx.doi.org/10.3390/s19183985
_version_ 1783454813718052864
author Griol, Amadeu
Peransi, Sergio
Rodrigo, Manuel
Hurtado, Juan
Bellieres, Laurent
Ivanova, Teodora
Zurita, David
Sánchez, Carles
Recuero, Sara
Hernández, Alejandro
Simón, Santiago
Balka, Gyula
Bossis, Ioannis
Capo, Alessandro
Camarca, Alessandra
D’Auria, Sabato
Varriale, Antonio
Giusti, Alessandro
author_facet Griol, Amadeu
Peransi, Sergio
Rodrigo, Manuel
Hurtado, Juan
Bellieres, Laurent
Ivanova, Teodora
Zurita, David
Sánchez, Carles
Recuero, Sara
Hernández, Alejandro
Simón, Santiago
Balka, Gyula
Bossis, Ioannis
Capo, Alessandro
Camarca, Alessandra
D’Auria, Sabato
Varriale, Antonio
Giusti, Alessandro
author_sort Griol, Amadeu
collection PubMed
description In this paper we introduce a field diagnostic device based on the combination of advanced bio-sensing and photonics technologies, to tackle emerging and endemic viruses causing swine epidemics, and consequently significant economic damage in farms. The device is based on the use of microring resonators fabricated in silicon nitride with CMOS compatible techniques. In the paper, the designed and fabricated photonic integrated circuit (PIC) sensors are presented and characterized, showing an optimized performance in terms of optical losses (30 dB per ring) and extinction ration for ring resonances (15 dB). Furthermore, the results of an experiment for porcine circovirus 2 (PCV2) detection by using the developed biosensors are presented. Positive detection for different virus concentrations has been obtained. The device is currently under development in the framework of the EU Commission co-funded project SWINOSTICS.
format Online
Article
Text
id pubmed-6766991
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-67669912019-10-02 Design and Development of Photonic Biosensors for Swine Viral Diseases Detection Griol, Amadeu Peransi, Sergio Rodrigo, Manuel Hurtado, Juan Bellieres, Laurent Ivanova, Teodora Zurita, David Sánchez, Carles Recuero, Sara Hernández, Alejandro Simón, Santiago Balka, Gyula Bossis, Ioannis Capo, Alessandro Camarca, Alessandra D’Auria, Sabato Varriale, Antonio Giusti, Alessandro Sensors (Basel) Article In this paper we introduce a field diagnostic device based on the combination of advanced bio-sensing and photonics technologies, to tackle emerging and endemic viruses causing swine epidemics, and consequently significant economic damage in farms. The device is based on the use of microring resonators fabricated in silicon nitride with CMOS compatible techniques. In the paper, the designed and fabricated photonic integrated circuit (PIC) sensors are presented and characterized, showing an optimized performance in terms of optical losses (30 dB per ring) and extinction ration for ring resonances (15 dB). Furthermore, the results of an experiment for porcine circovirus 2 (PCV2) detection by using the developed biosensors are presented. Positive detection for different virus concentrations has been obtained. The device is currently under development in the framework of the EU Commission co-funded project SWINOSTICS. MDPI 2019-09-15 /pmc/articles/PMC6766991/ /pubmed/31540156 http://dx.doi.org/10.3390/s19183985 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Griol, Amadeu
Peransi, Sergio
Rodrigo, Manuel
Hurtado, Juan
Bellieres, Laurent
Ivanova, Teodora
Zurita, David
Sánchez, Carles
Recuero, Sara
Hernández, Alejandro
Simón, Santiago
Balka, Gyula
Bossis, Ioannis
Capo, Alessandro
Camarca, Alessandra
D’Auria, Sabato
Varriale, Antonio
Giusti, Alessandro
Design and Development of Photonic Biosensors for Swine Viral Diseases Detection
title Design and Development of Photonic Biosensors for Swine Viral Diseases Detection
title_full Design and Development of Photonic Biosensors for Swine Viral Diseases Detection
title_fullStr Design and Development of Photonic Biosensors for Swine Viral Diseases Detection
title_full_unstemmed Design and Development of Photonic Biosensors for Swine Viral Diseases Detection
title_short Design and Development of Photonic Biosensors for Swine Viral Diseases Detection
title_sort design and development of photonic biosensors for swine viral diseases detection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766991/
https://www.ncbi.nlm.nih.gov/pubmed/31540156
http://dx.doi.org/10.3390/s19183985
work_keys_str_mv AT griolamadeu designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT peransisergio designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT rodrigomanuel designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT hurtadojuan designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT belliereslaurent designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT ivanovateodora designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT zuritadavid designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT sanchezcarles designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT recuerosara designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT hernandezalejandro designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT simonsantiago designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT balkagyula designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT bossisioannis designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT capoalessandro designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT camarcaalessandra designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT dauriasabato designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT varrialeantonio designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection
AT giustialessandro designanddevelopmentofphotonicbiosensorsforswineviraldiseasesdetection