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Design and Development of Photonic Biosensors for Swine Viral Diseases Detection
In this paper we introduce a field diagnostic device based on the combination of advanced bio-sensing and photonics technologies, to tackle emerging and endemic viruses causing swine epidemics, and consequently significant economic damage in farms. The device is based on the use of microring resonat...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766991/ https://www.ncbi.nlm.nih.gov/pubmed/31540156 http://dx.doi.org/10.3390/s19183985 |
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author | Griol, Amadeu Peransi, Sergio Rodrigo, Manuel Hurtado, Juan Bellieres, Laurent Ivanova, Teodora Zurita, David Sánchez, Carles Recuero, Sara Hernández, Alejandro Simón, Santiago Balka, Gyula Bossis, Ioannis Capo, Alessandro Camarca, Alessandra D’Auria, Sabato Varriale, Antonio Giusti, Alessandro |
author_facet | Griol, Amadeu Peransi, Sergio Rodrigo, Manuel Hurtado, Juan Bellieres, Laurent Ivanova, Teodora Zurita, David Sánchez, Carles Recuero, Sara Hernández, Alejandro Simón, Santiago Balka, Gyula Bossis, Ioannis Capo, Alessandro Camarca, Alessandra D’Auria, Sabato Varriale, Antonio Giusti, Alessandro |
author_sort | Griol, Amadeu |
collection | PubMed |
description | In this paper we introduce a field diagnostic device based on the combination of advanced bio-sensing and photonics technologies, to tackle emerging and endemic viruses causing swine epidemics, and consequently significant economic damage in farms. The device is based on the use of microring resonators fabricated in silicon nitride with CMOS compatible techniques. In the paper, the designed and fabricated photonic integrated circuit (PIC) sensors are presented and characterized, showing an optimized performance in terms of optical losses (30 dB per ring) and extinction ration for ring resonances (15 dB). Furthermore, the results of an experiment for porcine circovirus 2 (PCV2) detection by using the developed biosensors are presented. Positive detection for different virus concentrations has been obtained. The device is currently under development in the framework of the EU Commission co-funded project SWINOSTICS. |
format | Online Article Text |
id | pubmed-6766991 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-67669912019-10-02 Design and Development of Photonic Biosensors for Swine Viral Diseases Detection Griol, Amadeu Peransi, Sergio Rodrigo, Manuel Hurtado, Juan Bellieres, Laurent Ivanova, Teodora Zurita, David Sánchez, Carles Recuero, Sara Hernández, Alejandro Simón, Santiago Balka, Gyula Bossis, Ioannis Capo, Alessandro Camarca, Alessandra D’Auria, Sabato Varriale, Antonio Giusti, Alessandro Sensors (Basel) Article In this paper we introduce a field diagnostic device based on the combination of advanced bio-sensing and photonics technologies, to tackle emerging and endemic viruses causing swine epidemics, and consequently significant economic damage in farms. The device is based on the use of microring resonators fabricated in silicon nitride with CMOS compatible techniques. In the paper, the designed and fabricated photonic integrated circuit (PIC) sensors are presented and characterized, showing an optimized performance in terms of optical losses (30 dB per ring) and extinction ration for ring resonances (15 dB). Furthermore, the results of an experiment for porcine circovirus 2 (PCV2) detection by using the developed biosensors are presented. Positive detection for different virus concentrations has been obtained. The device is currently under development in the framework of the EU Commission co-funded project SWINOSTICS. MDPI 2019-09-15 /pmc/articles/PMC6766991/ /pubmed/31540156 http://dx.doi.org/10.3390/s19183985 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Griol, Amadeu Peransi, Sergio Rodrigo, Manuel Hurtado, Juan Bellieres, Laurent Ivanova, Teodora Zurita, David Sánchez, Carles Recuero, Sara Hernández, Alejandro Simón, Santiago Balka, Gyula Bossis, Ioannis Capo, Alessandro Camarca, Alessandra D’Auria, Sabato Varriale, Antonio Giusti, Alessandro Design and Development of Photonic Biosensors for Swine Viral Diseases Detection |
title | Design and Development of Photonic Biosensors for Swine Viral Diseases Detection |
title_full | Design and Development of Photonic Biosensors for Swine Viral Diseases Detection |
title_fullStr | Design and Development of Photonic Biosensors for Swine Viral Diseases Detection |
title_full_unstemmed | Design and Development of Photonic Biosensors for Swine Viral Diseases Detection |
title_short | Design and Development of Photonic Biosensors for Swine Viral Diseases Detection |
title_sort | design and development of photonic biosensors for swine viral diseases detection |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766991/ https://www.ncbi.nlm.nih.gov/pubmed/31540156 http://dx.doi.org/10.3390/s19183985 |
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