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Selectivity through discriminatory induced fit enables switching of NAD(P)H coenzyme specificity in Old Yellow Enzyme ene‐reductases

Most ene‐reductases belong to the Old Yellow Enzyme (OYE) family of flavin‐dependent oxidoreductases. OYEs use nicotinamide coenzymes as hydride donors to catalyze the reduction of alkenes that contain an electron‐withdrawing group. There have been many investigations of the structures and catalytic...

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Detalles Bibliográficos
Autores principales:	Iorgu, Andreea I., Hedison, Tobias M., Hay, Sam, Scrutton, Nigel S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Editor's Choice
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767020/ https://www.ncbi.nlm.nih.gov/pubmed/31033202 http://dx.doi.org/10.1111/febs.14862

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