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CLEFMA Activates the Extrinsic and Intrinsic Apoptotic Processes through JNK1/2 and p38 Pathways in Human Osteosarcoma Cells

Due to the poor prognosis of metastatic osteosarcoma, chemotherapy is usually employed in the adjuvant situation to improve the prognosis and the chances of long-term survival. 4-[3,5-Bis(2-chlorobenzylidene)-4-oxo-piperidine-1-yl]-4-oxo-2-butenoic acid (CLEFMA) is a synthetic analog of curcumin and...

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Detalles Bibliográficos
Autores principales:	Yang, Jia-Sin, Lin, Renn-Chia, Hsieh, Yi-Hsien, Wu, Heng-Hsiung, Li, Geng-Chung, Lin, Ya-Chiu, Yang, Shun-Fa, Lu, Ko-Hsiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767181/ https://www.ncbi.nlm.nih.gov/pubmed/31505816 http://dx.doi.org/10.3390/molecules24183280

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