Investigation of Metal-Organic Framework-5 (MOF-5) as an Antitumor Drug Oridonin Sustained Release Carrier

Oridonin (ORI) is a natural active ingredient with strong anticancer activity. But its clinical use is restricted due to its poor water solubility, short half-life, and low bioavailability. The aim of this study is to utilize the metal organic framework material MOF-5 to load ORI in order to improve...

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Detalles Bibliográficos
Autores principales: Chen, Gongsen, Luo, Juyuan, Cai, Mengru, Qin, Liuying, Wang, Yibo, Gao, Lili, Huang, Pingqing, Yu, Yingchao, Ding, Yangming, Dong, Xiaoxv, Yin, Xingbin, Ni, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767262/
https://www.ncbi.nlm.nih.gov/pubmed/31527488
http://dx.doi.org/10.3390/molecules24183369

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