Design of Peptidomimetic Functionalized Cholesterol Based Lipid Nanoparticles for Efficient Delivery of Therapeutic Nucleic Acids

Lipid nanoparticles (LNP) are the most potent carriers for the delivery of nucleic acid-based therapeutics. The first FDA approved a short interfering RNA (siRNA) drug that uses a cationic LNP system for the delivery of siRNA against human transthyretin (hTTR). However, preparation of such LNP invol...

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Detalles Bibliográficos
Autores principales: Ehexige, Ehexige, Ganbold, Tsogzolmaa, Yu, Xiang, Han, Shuqin, Baigude, Huricha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767268/
https://www.ncbi.nlm.nih.gov/pubmed/31546908
http://dx.doi.org/10.3390/molecules24183413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767268/
https://www.ncbi.nlm.nih.gov/pubmed/31546908
http://dx.doi.org/10.3390/molecules24183413

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