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Drug Metabolite Cluster-Based Data-Mining Method for Comprehensive Metabolism Study of 5-hydroxy-6,7,3′,4′-tetramethoxyflavone in Rats

The screening of drug metabolites in biological matrixes and structural characterization based on product ion spectra is among the most important, but also the most challenging due to the significant interferences from endogenous species. Traditionally, metabolite detection is accomplished primarily...

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Detalles Bibliográficos
Autores principales: Wang, Yuqi, Mei, Xiaodan, Liu, Zihan, Li, Jie, Zhang, Xiaoxin, Lang, Shuang, Dai, Long, Zhang, Jiayu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767304/
https://www.ncbi.nlm.nih.gov/pubmed/31505804
http://dx.doi.org/10.3390/molecules24183278