Enantiospecific Pharmacogenomics of Fluvastatin

The aim of this study was to investigate how variability in multiple genes related to pharmacokinetics affects fluvastatin exposure. We determined fluvastatin enantiomer pharmacokinetics and sequenced 379 pharmacokinetic genes in 200 healthy volunteers. CYP2C9*3 associated with significantly increas...

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Detalles Bibliográficos
Autores principales: Hirvensalo, Päivi, Tornio, Aleksi, Neuvonen, Mikko, Kiander, Wilma, Kidron, Heidi, Paile‐Hyvärinen, Maria, Tapaninen, Tuija, Backman, Janne T., Niemi, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767327/
https://www.ncbi.nlm.nih.gov/pubmed/30989645
http://dx.doi.org/10.1002/cpt.1463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767327/
https://www.ncbi.nlm.nih.gov/pubmed/30989645
http://dx.doi.org/10.1002/cpt.1463

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