YWHAZ amplification/overexpression defines aggressive bladder cancer and contributes to chemo‐/radio‐resistance by suppressing caspase‐mediated apoptosis

The objective of this study was to characterize the oncogenic actions of a recently identified cancer‐associated gene YWHAZ (also named as 14‐3‐3 ζ/δ) in urothelial carcinomas of the urinary bladder (UCUB). A genome‐wide study revealed YWHAZ to be involved in the amplicon at 8q22.3, and its genetic...

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Detalles Bibliográficos
Autores principales: Yu, Chia‐Cheng, Li, Chien‐Feng, Chen, I‐Hsuan, Lai, Ming‐Tsung, Lin, Zi‐Jun, Korla, Praveen K, Chai, Chee‐Yin, Ko, Grace, Chen, Chih‐Mei, Hwang, Tritium, Lee, Shan‐Chih, Sheu, Jim J‐C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767422/
https://www.ncbi.nlm.nih.gov/pubmed/30945298
http://dx.doi.org/10.1002/path.5274

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