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In search of disorders: internalizing symptom networks in a large clinical sample

BACKGROUND: The co‐occurrence of internalizing disorders is a common form of psychiatric comorbidity, raising questions about the boundaries between these diagnostic categories. We employ network psychometrics in order to: (a) determine whether internalizing symptoms cluster in a manner reflecting D...

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Detalles Bibliográficos
Autores principales: McElroy, Eoin, Patalay, Praveetha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767473/
https://www.ncbi.nlm.nih.gov/pubmed/30900257
http://dx.doi.org/10.1111/jcpp.13044
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author McElroy, Eoin
Patalay, Praveetha
author_facet McElroy, Eoin
Patalay, Praveetha
author_sort McElroy, Eoin
collection PubMed
description BACKGROUND: The co‐occurrence of internalizing disorders is a common form of psychiatric comorbidity, raising questions about the boundaries between these diagnostic categories. We employ network psychometrics in order to: (a) determine whether internalizing symptoms cluster in a manner reflecting DSM diagnostic criteria, (b) gauge how distinct these diagnostic clusters are and (c) examine whether this network structure changes from childhood to early and then late adolescence. METHOD: Symptom‐level data were obtained for service users in publicly funded mental health services in England between 2011 and 2015 (N = 37,162). A symptom network (i.e. Gaussian graphical model) was estimated, and a community detection algorithm was used to explore the clustering of symptoms. RESULTS: The estimated network was densely connected and characterized by a multitude of weak associations between symptoms. Six communities of symptoms were identified; however, they were weakly demarcated. Two of these communities corresponded to social phobia and panic disorder, and four did not clearly correspond with DSM diagnostic categories. The network structure was largely consistent by sex and across three age groups (8–11, 12–14 and 15–18 years). Symptom connectivity in the two older age groups was significantly greater compared to the youngest group and there were differences in centrality across the age groups, highlighting the age‐specific relevance of certain symptoms. CONCLUSIONS: These findings clearly demonstrate the interconnected nature of internalizing symptoms, challenging the view that such pathology takes the form of distinct disorders.
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spelling pubmed-67674732019-10-03 In search of disorders: internalizing symptom networks in a large clinical sample McElroy, Eoin Patalay, Praveetha J Child Psychol Psychiatry Original Articles BACKGROUND: The co‐occurrence of internalizing disorders is a common form of psychiatric comorbidity, raising questions about the boundaries between these diagnostic categories. We employ network psychometrics in order to: (a) determine whether internalizing symptoms cluster in a manner reflecting DSM diagnostic criteria, (b) gauge how distinct these diagnostic clusters are and (c) examine whether this network structure changes from childhood to early and then late adolescence. METHOD: Symptom‐level data were obtained for service users in publicly funded mental health services in England between 2011 and 2015 (N = 37,162). A symptom network (i.e. Gaussian graphical model) was estimated, and a community detection algorithm was used to explore the clustering of symptoms. RESULTS: The estimated network was densely connected and characterized by a multitude of weak associations between symptoms. Six communities of symptoms were identified; however, they were weakly demarcated. Two of these communities corresponded to social phobia and panic disorder, and four did not clearly correspond with DSM diagnostic categories. The network structure was largely consistent by sex and across three age groups (8–11, 12–14 and 15–18 years). Symptom connectivity in the two older age groups was significantly greater compared to the youngest group and there were differences in centrality across the age groups, highlighting the age‐specific relevance of certain symptoms. CONCLUSIONS: These findings clearly demonstrate the interconnected nature of internalizing symptoms, challenging the view that such pathology takes the form of distinct disorders. John Wiley and Sons Inc. 2019-03-21 2019-08 /pmc/articles/PMC6767473/ /pubmed/30900257 http://dx.doi.org/10.1111/jcpp.13044 Text en © 2019 The Authors. Journal of Child Psychology and Psychiatry published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
McElroy, Eoin
Patalay, Praveetha
In search of disorders: internalizing symptom networks in a large clinical sample
title In search of disorders: internalizing symptom networks in a large clinical sample
title_full In search of disorders: internalizing symptom networks in a large clinical sample
title_fullStr In search of disorders: internalizing symptom networks in a large clinical sample
title_full_unstemmed In search of disorders: internalizing symptom networks in a large clinical sample
title_short In search of disorders: internalizing symptom networks in a large clinical sample
title_sort in search of disorders: internalizing symptom networks in a large clinical sample
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767473/
https://www.ncbi.nlm.nih.gov/pubmed/30900257
http://dx.doi.org/10.1111/jcpp.13044
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