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CRISPR‐Knockout Screen Identifies Dmap1 as a Regulator of Chemically Induced Reprogramming and Differentiation of Cardiac Progenitors

Direct in vivo reprogramming of cardiac fibroblasts into myocytes is an attractive therapeutic intervention in resolving myogenic deterioration. Current transgene‐dependent approaches can restore cardiac function, but dependence on retroviral delivery and persistent retention of transgenic sequences...

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Detalles Bibliográficos
Autores principales: Yu, Jason S. L., Palano, Giorgia, Lim, Cindy, Moggio, Aldo, Drowley, Lauren, Plowright, Alleyn T., Bohlooly‐Y, Mohammad, Rosen, Barry S., Hansson, Emil M., Wang, Qing‐Dong, Yusa, Kosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767549/
https://www.ncbi.nlm.nih.gov/pubmed/30932271
http://dx.doi.org/10.1002/stem.3012

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