Reviewing HIV-1 Gag Mutations in Protease Inhibitors Resistance: Insights for Possible Novel Gag Inhibitor Designs

HIV protease inhibitors against the viral protease are often hampered by drug resistance mutations in protease and in the viral substrate Gag. To overcome this drug resistance and inhibit viral maturation, targeting Gag alongside protease rather than targeting protease alone may be more efficient. I...

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Detalles Bibliográficos
Autores principales: Su, Chinh Tran-To, Koh, Darius Wen-Shuo, Gan, Samuel Ken-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767625/
https://www.ncbi.nlm.nih.gov/pubmed/31489889
http://dx.doi.org/10.3390/molecules24183243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767625/
https://www.ncbi.nlm.nih.gov/pubmed/31489889
http://dx.doi.org/10.3390/molecules24183243

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