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Reviewing HIV-1 Gag Mutations in Protease Inhibitors Resistance: Insights for Possible Novel Gag Inhibitor Designs
HIV protease inhibitors against the viral protease are often hampered by drug resistance mutations in protease and in the viral substrate Gag. To overcome this drug resistance and inhibit viral maturation, targeting Gag alongside protease rather than targeting protease alone may be more efficient. I...
Autores principales: | Su, Chinh Tran-To, Koh, Darius Wen-Shuo, Gan, Samuel Ken-En |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767625/ https://www.ncbi.nlm.nih.gov/pubmed/31489889 http://dx.doi.org/10.3390/molecules24183243 |
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