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Metabolic engineering with ATP-citrate lyase and nitrogen source supplementation improves itaconic acid production in Aspergillus niger

BACKGROUND: Bio-based production of organic acids promises to be an attractive alternative for the chemicals industry to substitute petrochemicals as building-block chemicals. In recent years, itaconic acid (IA, methylenesuccinic acid) has been established as a sustainable building-block chemical fo...

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Detalles Bibliográficos
Autores principales:	Hossain, Abeer H., van Gerven, Roy, Overkamp, Karin M., Lübeck, Peter S., Taşpınar, Hatice, Türker, Mustafa, Punt, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767652/ https://www.ncbi.nlm.nih.gov/pubmed/31583019 http://dx.doi.org/10.1186/s13068-019-1577-6

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