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Mirror finger patterns of apparent monozygotic twins and sib pairs with Schizophrenia

BACKGROUND: Although mirror images are noted in some twins, no such reports are available for twins and subjects with schizophrenia. AIM: The study was to assess the occurrence of mirror image finger patterns in apparent monozygotic twins with schizophrenia. Another objective was to elucidate these...

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Autores principales: Ponnudurai, R, Shajahan, I, Rani, A, Jayakar, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767825/
https://www.ncbi.nlm.nih.gov/pubmed/31579182
http://dx.doi.org/10.4103/psychiatry.IndianJPsychiatry_476_18
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author Ponnudurai, R
Shajahan, I
Rani, A
Jayakar, J
author_facet Ponnudurai, R
Shajahan, I
Rani, A
Jayakar, J
author_sort Ponnudurai, R
collection PubMed
description BACKGROUND: Although mirror images are noted in some twins, no such reports are available for twins and subjects with schizophrenia. AIM: The study was to assess the occurrence of mirror image finger patterns in apparent monozygotic twins with schizophrenia. Another objective was to elucidate these characteristics among sib pairs with schizophrenia for comparison with those of the twins. MATERIALS AND METHODS: Eight apparent monozygotic twin pairs and eight sib pairs with schizophrenia were investigated. The frequency of identical patterns in the right side finger of one twin and the corresponding left side finger of the other twin was assessed, and similarly on other sides. Similar assessment was made in sib pairs with schizophrenia and normal sib pairs. RESULTS: The left middle finger pattern of one of the twin pair was found to be the mirror image of the right middle finger of the other twin in all the twin pairs studied and so was in seven of the sib pairs with schizophrenia. These mirror images of sib pairs with schizophrenia was more than those of normal sib pairs. This difference was accentuated with significantly more of these patterns in the twins in comparison to those among normal sib pairs. Notably, no difference emerged between the sib pairs with schizophrenia and the twins in any of their finger pairs. CONCLUSION: Mirror images that are probably due to factors like abnormal genotypes and L- DNA, appear to be promising tools to study the etiology of schizophrenia.
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spelling pubmed-67678252019-10-02 Mirror finger patterns of apparent monozygotic twins and sib pairs with Schizophrenia Ponnudurai, R Shajahan, I Rani, A Jayakar, J Indian J Psychiatry Brief Research Communication BACKGROUND: Although mirror images are noted in some twins, no such reports are available for twins and subjects with schizophrenia. AIM: The study was to assess the occurrence of mirror image finger patterns in apparent monozygotic twins with schizophrenia. Another objective was to elucidate these characteristics among sib pairs with schizophrenia for comparison with those of the twins. MATERIALS AND METHODS: Eight apparent monozygotic twin pairs and eight sib pairs with schizophrenia were investigated. The frequency of identical patterns in the right side finger of one twin and the corresponding left side finger of the other twin was assessed, and similarly on other sides. Similar assessment was made in sib pairs with schizophrenia and normal sib pairs. RESULTS: The left middle finger pattern of one of the twin pair was found to be the mirror image of the right middle finger of the other twin in all the twin pairs studied and so was in seven of the sib pairs with schizophrenia. These mirror images of sib pairs with schizophrenia was more than those of normal sib pairs. This difference was accentuated with significantly more of these patterns in the twins in comparison to those among normal sib pairs. Notably, no difference emerged between the sib pairs with schizophrenia and the twins in any of their finger pairs. CONCLUSION: Mirror images that are probably due to factors like abnormal genotypes and L- DNA, appear to be promising tools to study the etiology of schizophrenia. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6767825/ /pubmed/31579182 http://dx.doi.org/10.4103/psychiatry.IndianJPsychiatry_476_18 Text en Copyright: © 2019 Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Brief Research Communication
Ponnudurai, R
Shajahan, I
Rani, A
Jayakar, J
Mirror finger patterns of apparent monozygotic twins and sib pairs with Schizophrenia
title Mirror finger patterns of apparent monozygotic twins and sib pairs with Schizophrenia
title_full Mirror finger patterns of apparent monozygotic twins and sib pairs with Schizophrenia
title_fullStr Mirror finger patterns of apparent monozygotic twins and sib pairs with Schizophrenia
title_full_unstemmed Mirror finger patterns of apparent monozygotic twins and sib pairs with Schizophrenia
title_short Mirror finger patterns of apparent monozygotic twins and sib pairs with Schizophrenia
title_sort mirror finger patterns of apparent monozygotic twins and sib pairs with schizophrenia
topic Brief Research Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767825/
https://www.ncbi.nlm.nih.gov/pubmed/31579182
http://dx.doi.org/10.4103/psychiatry.IndianJPsychiatry_476_18
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