Cerebral Amyloid Angiopathy Related Inflammation With Prominent Meningeal Involvement. A Report of 2 Cases

Cerebral amyloid angiopathy related inflammation (CAA-RI) is a rare form of CAA characterized by subacute encephalitic symptoms (cognitive decline, seizures, focal deficits) associated with extensive and confluent white matter lesions co-localizing with lobar microbleeds on brain MRI. We report two...

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Autores principales: Aghetti, Agnès, Sène, Damien, Polivka, Marc, Shor, Natalia, Lechtman, Sarah, Chabriat, Hugues, Jouvent, Eric, Guey, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768005/
https://www.ncbi.nlm.nih.gov/pubmed/31608002
http://dx.doi.org/10.3389/fneur.2019.00984
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author Aghetti, Agnès
Sène, Damien
Polivka, Marc
Shor, Natalia
Lechtman, Sarah
Chabriat, Hugues
Jouvent, Eric
Guey, Stéphanie
author_facet Aghetti, Agnès
Sène, Damien
Polivka, Marc
Shor, Natalia
Lechtman, Sarah
Chabriat, Hugues
Jouvent, Eric
Guey, Stéphanie
author_sort Aghetti, Agnès
collection PubMed
description Cerebral amyloid angiopathy related inflammation (CAA-RI) is a rare form of CAA characterized by subacute encephalitic symptoms (cognitive decline, seizures, focal deficits) associated with extensive and confluent white matter lesions co-localizing with lobar microbleeds on brain MRI. We report two cases of unusual CAA-RI mimicking meningoencephalitis but without typical brain lesions on FLAIR and T2(*) sequences. These 2 cases may extend the clinical spectrum of CAA-RI by suggesting the possible occurrence of quite purely meningeal forms of CAA-RI.
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spelling pubmed-67680052019-10-13 Cerebral Amyloid Angiopathy Related Inflammation With Prominent Meningeal Involvement. A Report of 2 Cases Aghetti, Agnès Sène, Damien Polivka, Marc Shor, Natalia Lechtman, Sarah Chabriat, Hugues Jouvent, Eric Guey, Stéphanie Front Neurol Neurology Cerebral amyloid angiopathy related inflammation (CAA-RI) is a rare form of CAA characterized by subacute encephalitic symptoms (cognitive decline, seizures, focal deficits) associated with extensive and confluent white matter lesions co-localizing with lobar microbleeds on brain MRI. We report two cases of unusual CAA-RI mimicking meningoencephalitis but without typical brain lesions on FLAIR and T2(*) sequences. These 2 cases may extend the clinical spectrum of CAA-RI by suggesting the possible occurrence of quite purely meningeal forms of CAA-RI. Frontiers Media S.A. 2019-09-23 /pmc/articles/PMC6768005/ /pubmed/31608002 http://dx.doi.org/10.3389/fneur.2019.00984 Text en Copyright © 2019 Aghetti, Sène, Polivka, Shor, Lechtman, Chabriat, Jouvent and Guey. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Aghetti, Agnès
Sène, Damien
Polivka, Marc
Shor, Natalia
Lechtman, Sarah
Chabriat, Hugues
Jouvent, Eric
Guey, Stéphanie
Cerebral Amyloid Angiopathy Related Inflammation With Prominent Meningeal Involvement. A Report of 2 Cases
title Cerebral Amyloid Angiopathy Related Inflammation With Prominent Meningeal Involvement. A Report of 2 Cases
title_full Cerebral Amyloid Angiopathy Related Inflammation With Prominent Meningeal Involvement. A Report of 2 Cases
title_fullStr Cerebral Amyloid Angiopathy Related Inflammation With Prominent Meningeal Involvement. A Report of 2 Cases
title_full_unstemmed Cerebral Amyloid Angiopathy Related Inflammation With Prominent Meningeal Involvement. A Report of 2 Cases
title_short Cerebral Amyloid Angiopathy Related Inflammation With Prominent Meningeal Involvement. A Report of 2 Cases
title_sort cerebral amyloid angiopathy related inflammation with prominent meningeal involvement. a report of 2 cases
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768005/
https://www.ncbi.nlm.nih.gov/pubmed/31608002
http://dx.doi.org/10.3389/fneur.2019.00984
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