Synthesis and antitumor activities of 3-substituted-analine derivatives: structure modifications of Tuv part of tubulysins

BACKGROUND: Tubulysins family is a kind of natural compound with potent, antitumor activity. To simplify the synthesis route and find new antitumor compounds is becoming a hotspot of research recent years. RESULTS: Starting from 3-nitrobenzoic acid, after 7 steps transformations, 12 new tubulysin an...

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Detalles Bibliográficos
Autores principales: Shao, Mingsha, Bai, Xinfa, Ma, Xuan, Yan, Ning, Yao, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768038/
https://www.ncbi.nlm.nih.gov/pubmed/30443866
http://dx.doi.org/10.1186/s13065-018-0483-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768038/
https://www.ncbi.nlm.nih.gov/pubmed/30443866
http://dx.doi.org/10.1186/s13065-018-0483-5

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