An integrated approach towards the development of novel antifungal agents containing thiadiazole: synthesis and a combined similarity search, homology modelling, molecular dynamics and molecular docking study

BACKGROUND: This study aims to synthesise and characterise novel compounds containing 2-amino-1,3,4-thiadiazole and their acyl derivatives and to investigate antifungal activities. Similarity search, molecular dynamics and molecular docking were also studied to find out a potential target and enligh...

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Detalles Bibliográficos
Autores principales: Er, Mustafa, Abounakhla, Abdulati Miftah, Tahtaci, Hakan, Bawah, Ali Hasin, Çınaroğlu, Süleyman Selim, Onaran, Abdurrahman, Ece, Abdulilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768040/
https://www.ncbi.nlm.nih.gov/pubmed/30470928
http://dx.doi.org/10.1186/s13065-018-0485-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768040/
https://www.ncbi.nlm.nih.gov/pubmed/30470928
http://dx.doi.org/10.1186/s13065-018-0485-3

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