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Modeling tool using neural networks for l(+)-lactic acid production by pellet-form Rhizopus oryzae NRRL 395 on biodiesel crude glycerol
Most chemical reactions produce unwanted by-products. In an effort to reduce environmental problems these by-products could be used to produce valuable organic chemicals. In biodiesel industry a huge amount of glycerol is generated, approximately 10% of the final product. The research group from Uni...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768043/ https://www.ncbi.nlm.nih.gov/pubmed/30499033 http://dx.doi.org/10.1186/s13065-018-0491-5 |
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author | Dulf, Eva-H. Vodnar, Dan Cristian Dulf, Francisc-V. |
author_facet | Dulf, Eva-H. Vodnar, Dan Cristian Dulf, Francisc-V. |
author_sort | Dulf, Eva-H. |
collection | PubMed |
description | Most chemical reactions produce unwanted by-products. In an effort to reduce environmental problems these by-products could be used to produce valuable organic chemicals. In biodiesel industry a huge amount of glycerol is generated, approximately 10% of the final product. The research group from University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca developed opportunities to produce l(+) lactic acid from the glycerol. The team is using the Rhizopus oryzae NRRL 395 bacteria for the fermentation of the glycerol. The purpose of the research is to improve the production of l(+) lactic acid in order to optimize the process. A predictive model obtained by neural networks is useful in this case. The main objective of the present work is to present the developed user-friendly application useful in modeling this fermentation process, in order to be used by people who are inexperienced with neural networks or specific software. Besides the interface for training of a new neural network in order to develop the model in some characteristic condition, the software also provides an interface for visualization of the results, useful in interpretation and as a tool for prediction. |
format | Online Article Text |
id | pubmed-6768043 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-67680432019-10-03 Modeling tool using neural networks for l(+)-lactic acid production by pellet-form Rhizopus oryzae NRRL 395 on biodiesel crude glycerol Dulf, Eva-H. Vodnar, Dan Cristian Dulf, Francisc-V. Chem Cent J Research Article Most chemical reactions produce unwanted by-products. In an effort to reduce environmental problems these by-products could be used to produce valuable organic chemicals. In biodiesel industry a huge amount of glycerol is generated, approximately 10% of the final product. The research group from University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca developed opportunities to produce l(+) lactic acid from the glycerol. The team is using the Rhizopus oryzae NRRL 395 bacteria for the fermentation of the glycerol. The purpose of the research is to improve the production of l(+) lactic acid in order to optimize the process. A predictive model obtained by neural networks is useful in this case. The main objective of the present work is to present the developed user-friendly application useful in modeling this fermentation process, in order to be used by people who are inexperienced with neural networks or specific software. Besides the interface for training of a new neural network in order to develop the model in some characteristic condition, the software also provides an interface for visualization of the results, useful in interpretation and as a tool for prediction. Springer International Publishing 2018-11-29 /pmc/articles/PMC6768043/ /pubmed/30499033 http://dx.doi.org/10.1186/s13065-018-0491-5 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Dulf, Eva-H. Vodnar, Dan Cristian Dulf, Francisc-V. Modeling tool using neural networks for l(+)-lactic acid production by pellet-form Rhizopus oryzae NRRL 395 on biodiesel crude glycerol |
title | Modeling tool using neural networks for l(+)-lactic acid production by pellet-form Rhizopus oryzae NRRL 395 on biodiesel crude glycerol |
title_full | Modeling tool using neural networks for l(+)-lactic acid production by pellet-form Rhizopus oryzae NRRL 395 on biodiesel crude glycerol |
title_fullStr | Modeling tool using neural networks for l(+)-lactic acid production by pellet-form Rhizopus oryzae NRRL 395 on biodiesel crude glycerol |
title_full_unstemmed | Modeling tool using neural networks for l(+)-lactic acid production by pellet-form Rhizopus oryzae NRRL 395 on biodiesel crude glycerol |
title_short | Modeling tool using neural networks for l(+)-lactic acid production by pellet-form Rhizopus oryzae NRRL 395 on biodiesel crude glycerol |
title_sort | modeling tool using neural networks for l(+)-lactic acid production by pellet-form rhizopus oryzae nrrl 395 on biodiesel crude glycerol |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768043/ https://www.ncbi.nlm.nih.gov/pubmed/30499033 http://dx.doi.org/10.1186/s13065-018-0491-5 |
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