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Synthesis, characterization, molecular docking, analgesic, antiplatelet and anticoagulant effects of dibenzylidene ketone derivatives

In this study dibenzylidene ketone derivatives (2E,5E)-2-(4-methoxybenzylidene)-5-(4-nitrobenzylidene) cyclopentanone (AK-1a) and (1E,4E)-4-(4-nitrobenzylidene)-1-(4-nitrophenyl) oct-1-en-3-one (AK-2a) were newly synthesized, inspired from curcuminoids natural origin. Novel scheme was used for synth...

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Detalles Bibliográficos
Autores principales: Ahmed, Tauqeer, Khan, Arif-ullah, Abbass, Muzaffar, Filho, Edson Rodrigues, Ud Din, Zia, Khan, Aslam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768048/
https://www.ncbi.nlm.nih.gov/pubmed/30523436
http://dx.doi.org/10.1186/s13065-018-0507-1