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TRPML1 and RAS-driven cancers – exploring a link with great therapeutic potential
Activating mutations in the RAS family of proto-oncogenes represent some of the leading causes of cancer. Unmitigated proliferation of cells harboring oncogenic RAS mutations is accompanied by a massive increase in cellular bioenergetic demands, which offers unique opportunities for therapeutic inte...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768051/ https://www.ncbi.nlm.nih.gov/pubmed/31526156 http://dx.doi.org/10.1080/19336950.2019.1666457 |