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Absence of the Lectin Activation Pathway of Complement Ameliorates Proteinuria-Induced Renal Injury

Proteinuria is an adverse prognostic feature in renal diseases. In proteinuric nephropathies, filtered proteins exert an injurious effect on the renal tubulointerstitium, resulting in inflammation and fibrosis. In the present study, we assessed to what extent complement activation via the lectin pat...

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Detalles Bibliográficos
Autores principales: Alghadban, Samy, Kenawy, Hany I., Dudler, Thomas, Schwaeble, Wilhelm J., Brunskill, Nigel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768126/
https://www.ncbi.nlm.nih.gov/pubmed/31608060
http://dx.doi.org/10.3389/fimmu.2019.02238