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Absence of the Lectin Activation Pathway of Complement Ameliorates Proteinuria-Induced Renal Injury
Proteinuria is an adverse prognostic feature in renal diseases. In proteinuric nephropathies, filtered proteins exert an injurious effect on the renal tubulointerstitium, resulting in inflammation and fibrosis. In the present study, we assessed to what extent complement activation via the lectin pat...
Autores principales: | Alghadban, Samy, Kenawy, Hany I., Dudler, Thomas, Schwaeble, Wilhelm J., Brunskill, Nigel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768126/ https://www.ncbi.nlm.nih.gov/pubmed/31608060 http://dx.doi.org/10.3389/fimmu.2019.02238 |
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