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A MetAP2 inhibitor blocks adipogenesis, yet improves glucose uptake in cells

Adipose tissue expansion involves angiogenesis to remodel its capillary network. The enzymemethionine aminopeptidase 2(MetAP2) promotes angiogenesis.MetAP2 inhibitors suppress angiogenesis and have potential anti-obesity effect. However, impairment in adipose tissue expansion is also linked with imp...

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Detalles Bibliográficos
Autores principales: Siddik, Md Abu Bakkar, Das, Bhaskar C., Weiss, Louis, Dhurandhar, Nikhil V., Hegde, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768232/
https://www.ncbi.nlm.nih.gov/pubmed/31264515
http://dx.doi.org/10.1080/21623945.2019.1636627