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Breast cancer-released exosomes trigger cancer-associated cachexia to promote tumor progression
Cancer-secreted exosomes are emerging mediators of cancer-associated cachexia. Here, we show that miR-155 secreted by breast cancer cells is a potent role on the catabolism of adipocytes and muscle cells through targeting the PPARγ. After cocultivated with mature adipocytes or C2C12, tumour cells ex...
Autores principales: | Wu, Qi, Sun, Si, Li, Zhiyu, Yang, Qian, Li, Bei, Zhu, Shan, Wang, Lijun, Wu, Juan, Yuan, Jingping, Wang, Changhua, Li, Juanjuan, Sun, Shengrong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768245/ https://www.ncbi.nlm.nih.gov/pubmed/30474469 http://dx.doi.org/10.1080/21623945.2018.1551688 |
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