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Spontaneous lymphoblastoid cell lines from patients with Epstein-Barr virus infection show highly variable proliferation characteristics that correlate with the expression levels of viral microRNAs
The Epstein-Barr virus (EBV) induces B-cell proliferation with high efficiency through expression of latent proteins and microRNAs. This process takes place in vivo soon after infection, presumably to expand the virus reservoir, but can also induce pathologies, e.g. an infectious mononucleosis (IM)...
Autores principales: | Delecluse, Susanne, Yu, Jiyang, Bernhardt, Katharina, Haar, Janina, Poirey, Remy, Tsai, Ming-Han, Kiblawi, Rama, Kopp-Schneider, Annette, Schnitzler, Paul, Zeier, Martin, Dreger, Peter, Wuchter, Patrick, Bulut, Olcay Cem, Behrends, Uta, Delecluse, Henri-Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768455/ https://www.ncbi.nlm.nih.gov/pubmed/31568538 http://dx.doi.org/10.1371/journal.pone.0222847 |
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