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Spontaneous lymphoblastoid cell lines from patients with Epstein-Barr virus infection show highly variable proliferation characteristics that correlate with the expression levels of viral microRNAs

The Epstein-Barr virus (EBV) induces B-cell proliferation with high efficiency through expression of latent proteins and microRNAs. This process takes place in vivo soon after infection, presumably to expand the virus reservoir, but can also induce pathologies, e.g. an infectious mononucleosis (IM)...

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Detalles Bibliográficos
Autores principales: Delecluse, Susanne, Yu, Jiyang, Bernhardt, Katharina, Haar, Janina, Poirey, Remy, Tsai, Ming-Han, Kiblawi, Rama, Kopp-Schneider, Annette, Schnitzler, Paul, Zeier, Martin, Dreger, Peter, Wuchter, Patrick, Bulut, Olcay Cem, Behrends, Uta, Delecluse, Henri-Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768455/
https://www.ncbi.nlm.nih.gov/pubmed/31568538
http://dx.doi.org/10.1371/journal.pone.0222847

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