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EGFR Signaling Termination via Numb Trafficking in Ependymal Progenitors Controls Postnatal Neurogenic Niche Differentiation

Specialized microenvironments, called niches, control adult stem cell proliferation and differentiation. The brain lateral ventricular (LV) neurogenic niche is generated from distinct postnatal radial glial progenitors (pRGPs), giving rise to adult neural stem cells (NSCs) and niche ependymal cells...

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Detalles Bibliográficos
Autores principales: Abdi, Khadar, Neves, Gabriel, Pyun, Joon, Kiziltug, Emre, Ahrens, Angelica, Kuo, Chay T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768562/
https://www.ncbi.nlm.nih.gov/pubmed/31433979
http://dx.doi.org/10.1016/j.celrep.2019.07.056

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