Cargando…
A ubiquitin-like domain controls protein kinase D dimerization and activation by trans-autophosphorylation
Protein kinase D (PKD) is an essential Ser/Thr kinase in animals and controls a variety of diverse cellular functions, including vesicle trafficking and mitogenesis. PKD is activated by recruitment to membranes containing the lipid second messenger diacylglycerol (DAG) and subsequent phosphorylation...
Autores principales: | Elsner, Daniel J., Siess, Katharina M., Gossenreiter, Thomas, Hartl, Markus, Leonard, Thomas A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768651/ https://www.ncbi.nlm.nih.gov/pubmed/31406020 http://dx.doi.org/10.1074/jbc.RA119.008713 |
Ejemplares similares
-
Redox-dependent dimerization of p38α mitogen-activated protein kinase with mitogen-activated protein kinase kinase 3
por: Bassi, Rekha, et al.
Publicado: (2017) -
Neuroepithelial Transforming Gene 1 (Net1) Binds to Caspase Activation and Recruitment Domain (CARD)- and Membrane-associated Guanylate Kinase-like Domain-containing (CARMA) Proteins and Regulates Nuclear Factor κB Activation
por: Vessichelli, Mariangela, et al.
Publicado: (2012) -
Direct and Indirect Control of Mitogen-activated Protein Kinase Pathway-associated Components, BRAP/IMP E3 Ubiquitin Ligase and CRAF/RAF1 Kinase, by the Deubiquitylating Enzyme USP15
por: Hayes, Sebastian D., et al.
Publicado: (2012) -
Identification of two distinct peptide-binding pockets in the SH3 domain of human mixed-lineage kinase 3
por: Kokoszka, Malgorzata E., et al.
Publicado: (2018) -
Targeting Toll-like Receptor (TLR) Signaling by Toll/Interleukin-1 Receptor (TIR) Domain-containing Adapter Protein/MyD88 Adapter-like (TIRAP/Mal)-derived Decoy Peptides
por: Couture, Leah A., et al.
Publicado: (2012)