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The NKCC1 antagonist bumetanide mitigates interneuronopathy associated with ethanol exposure in utero

Prenatal exposure to ethanol induces aberrant tangential migration of corticopetal GABAergic interneurons, and long-term alterations in the form and function of the prefrontal cortex. We have hypothesized that interneuronopathy contributes significantly to the pathoetiology of fetal alcohol spectrum...

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Detalles Bibliográficos
Autores principales: Skorput, Alexander GJ, Lee, Stephanie M, Yeh, Pamela WL, Yeh, Hermes H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768659/
https://www.ncbi.nlm.nih.gov/pubmed/31545168
http://dx.doi.org/10.7554/eLife.48648