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In situ analysis of Her2 DNA and RNA in retinoblastoma and adjacent retina

Retinoblastoma (RB) is an ocular tumor of early childhood. Current treatments attempt to preserve visual function, but may spare chemoresistant tumor cells. One potential therapeutic target for RB is HER2, (ERBB2), expressed in RB in truncated form. In this study, we tested the hypothesis that Her2...

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Detalles Bibliográficos
Autores principales: Seigel, Gail M, Shah, Dhaval K, Mendoza, Pia, Szalai, Ezster, Grossniklaus, Hans, Song, Yinghui, Shan, Jidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768847/
https://www.ncbi.nlm.nih.gov/pubmed/31608299
http://dx.doi.org/10.18632/oncoscience.489

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