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A Prospective Clinical Study Characterizing the Influence of Morbid Obesity on the Pharmacokinetics of Gentamicin: Towards Individualized Dosing in Obese Patients

BACKGROUND AND OBJECTIVE: Gentamicin is an aminoglycoside antibiotic predominantly used in bloodstream infections. Although the prevalence of obesity is increasing dramatically, there is no consensus on how to adjust the dose in obese individuals. In this prospective clinical study, we study the pha...

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Detalles Bibliográficos
Autores principales:	Smit, Cornelis, Wasmann, Roeland E., Goulooze, Sebastiaan C., Hazebroek, Eric J., Van Dongen, Eric P. A., Burgers, Desiree M. T., Mouton, Johan W., Brüggemann, Roger J. M., Knibbe, Catherijne A. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2019
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768900/ https://www.ncbi.nlm.nih.gov/pubmed/31016671 http://dx.doi.org/10.1007/s40262-019-00762-4

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