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Corticosteroid-Binding Globulin is expressed in the adrenal gland and its absence impairs corticosterone synthesis and secretion in a sex-dependent manner
Corticosteroid-binding globulin (CBG) is synthesized by the liver and secreted into the bloodstream where binds to glucocorticoids. Thus CBG has the role of glucocorticoid transport and free hormone control. In addition, CBG has been detected in some extrahepatic tissues without a known role. CBG-de...
Autores principales: | Gulfo, José, Castel, Ricard, Ledda, Angelo, Romero, María del Mar, Esteve, Montserrat, Grasa, Mar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769001/ https://www.ncbi.nlm.nih.gov/pubmed/31570737 http://dx.doi.org/10.1038/s41598-019-50355-1 |
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