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M1 muscarinic receptor is a key target of neuroprotection, neuroregeneration and memory recovery by i-Extract from Withania somnifera

Memory loss is one of the most tragic symptoms of Alzheimer’s disease. Our laboratory has recently demonstrated that ‘i-Extract’ of Ashwagandha (Withania somnifera) restores memory loss in scopolamine (SC)-induced mice. The prime target of i-Extract is obscure. We hypothesize that i-Extract may prim...

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Detalles Bibliográficos
Autores principales: Konar, Arpita, Gupta, Richa, Shukla, Rajendra K., Maloney, Bryan, Khanna, Vinay K., Wadhwa, Renu, Lahiri, Debomoy K., Thakur, Mahendra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769020/
https://www.ncbi.nlm.nih.gov/pubmed/31570736
http://dx.doi.org/10.1038/s41598-019-48238-6