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Nobiletin-loaded micelles reduce ovariectomy-induced bone loss by suppressing osteoclastogenesis

BACKGROUND: Nobiletin (NOB), a polymethoxy flavonoid, possesses anti-cancer and anti-inflammatory activities, has been reported that it played role in anti-osteoporosis treatment. However, previous research did not focus on practical use due to lack of hydrophilicity and cytotoxicity at high concent...

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Detalles Bibliográficos
Autores principales: Wang, Yabing, Xie, Jian, Ai, Zexin, Su, Jiansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769031/
https://www.ncbi.nlm.nih.gov/pubmed/31576127
http://dx.doi.org/10.2147/IJN.S213724