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Comprehensive Evaluation of Organotypic and Microphysiological Liver Models for Prediction of Drug-Induced Liver Injury

Drug-induced liver injury (DILI) is a major concern for the pharmaceutical industry and constitutes one of the most important reasons for the termination of promising drug development projects. Reliable prediction of DILI liability in preclinical stages is difficult, as current experimental model sy...

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Detalles Bibliográficos
Autores principales:	Zhou, Yitian, Shen, Joanne X., Lauschke, Volker M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769037/ https://www.ncbi.nlm.nih.gov/pubmed/31616302 http://dx.doi.org/10.3389/fphar.2019.01093

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