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Mesenchymal Stem Cell Secretion of SDF-1α Modulates Endothelial Function in Dilated Cardiomyopathy

BACKGROUND: Endothelial dysfunction contributes to the pathophysiology of dilated cardiomyopathy (DCM). Allogeneic but not autologous mesenchymal stem cells (MSCs) improve endothelial function in DCM patients. We hypothesized that these effects are modulated by release of stromal derived factor-1α (...

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Detalles Bibliográficos
Autores principales:	Premer, Courtney, Wanschel, Amarylis, Porras, Valeria, Balkan, Wayne, Legendre-Hyldig, Tatiana, Saltzman, Russell G., Dong, Chunming, Schulman, Ivonne Hernandez, Hare, Joshua M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769040/ https://www.ncbi.nlm.nih.gov/pubmed/31616309 http://dx.doi.org/10.3389/fphys.2019.01182

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