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Amphiphilic nanogels: influence of surface hydrophobicity on protein corona, biocompatibility and cellular uptake

BACKGROUND AND PURPOSE: Nanogels (NGs) are promising drug delivery tools but are typically limited to hydrophilic drugs. Many potential new drugs are hydrophobic. Our study systematically investigates amphiphilic NGs with varying hydrophobicity, but similar colloidal features to ensure comparability...

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Detalles Bibliográficos
Autores principales: Bewersdorff, Tony, Gruber, Alexandra, Eravci, Murat, Dumbani, Malti, Klinger, Daniel, Haase, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769055/
https://www.ncbi.nlm.nih.gov/pubmed/31576128
http://dx.doi.org/10.2147/IJN.S215935