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Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex
Electrical stimulation of the primary somatosensory cortex using intracranial electrodes is crucial for the evocation of artificial somatosensations, typically tactile sensations associated with specific regions of the body, in brain-machine interface (BMI) applications. The qualitative characterist...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769168/ https://www.ncbi.nlm.nih.gov/pubmed/31607854 http://dx.doi.org/10.3389/fnins.2019.01019 |
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author | Kirin, St. Clair Yanagisawa, Takufumi Oshino, Satoru Edakawa, Kohtaroh Tanaka, Masataka Kishima, Haruhiko Nishimura, Yukio |
author_facet | Kirin, St. Clair Yanagisawa, Takufumi Oshino, Satoru Edakawa, Kohtaroh Tanaka, Masataka Kishima, Haruhiko Nishimura, Yukio |
author_sort | Kirin, St. Clair |
collection | PubMed |
description | Electrical stimulation of the primary somatosensory cortex using intracranial electrodes is crucial for the evocation of artificial somatosensations, typically tactile sensations associated with specific regions of the body, in brain-machine interface (BMI) applications. The qualitative characteristics of these artificially evoked somatosensations has been well documented. As of yet, however, the quantitative aspects of these evoked somatosensations, that is to say the quantitative relationship between intensity of electrical stimulation and perceived intensity of the resultant somatosensation remains obscure. This study aimed to explore this quantitative relationship by surface electrical stimulation of the primary somatosensory cortex in two human participants undergoing electrocorticographic monitoring prior to surgical treatment of intractable epilepsy. Electrocorticogram electrodes on the primary somatosensory cortical surface were stimulated with varying current intensities, and a visual analogue scale was employed to provide a quantitative measure of intensity of the evoked sensations. Evoked sensations included those of the thumb, tongue, and hand. A clear linear relationship between current intensity and perceived intensity of sensation was observed. These findings provide novel insight into the quantitative nature of primary somatosensory cortex electrical stimulation-evoked sensation for development of somatosensory neuroprosthetics for clinical use. |
format | Online Article Text |
id | pubmed-6769168 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-67691682019-10-11 Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex Kirin, St. Clair Yanagisawa, Takufumi Oshino, Satoru Edakawa, Kohtaroh Tanaka, Masataka Kishima, Haruhiko Nishimura, Yukio Front Neurosci Neuroscience Electrical stimulation of the primary somatosensory cortex using intracranial electrodes is crucial for the evocation of artificial somatosensations, typically tactile sensations associated with specific regions of the body, in brain-machine interface (BMI) applications. The qualitative characteristics of these artificially evoked somatosensations has been well documented. As of yet, however, the quantitative aspects of these evoked somatosensations, that is to say the quantitative relationship between intensity of electrical stimulation and perceived intensity of the resultant somatosensation remains obscure. This study aimed to explore this quantitative relationship by surface electrical stimulation of the primary somatosensory cortex in two human participants undergoing electrocorticographic monitoring prior to surgical treatment of intractable epilepsy. Electrocorticogram electrodes on the primary somatosensory cortical surface were stimulated with varying current intensities, and a visual analogue scale was employed to provide a quantitative measure of intensity of the evoked sensations. Evoked sensations included those of the thumb, tongue, and hand. A clear linear relationship between current intensity and perceived intensity of sensation was observed. These findings provide novel insight into the quantitative nature of primary somatosensory cortex electrical stimulation-evoked sensation for development of somatosensory neuroprosthetics for clinical use. Frontiers Media S.A. 2019-09-24 /pmc/articles/PMC6769168/ /pubmed/31607854 http://dx.doi.org/10.3389/fnins.2019.01019 Text en Copyright © 2019 Kirin, Yanagisawa, Oshino, Edakawa, Tanaka, Kishima and Nishimura. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Kirin, St. Clair Yanagisawa, Takufumi Oshino, Satoru Edakawa, Kohtaroh Tanaka, Masataka Kishima, Haruhiko Nishimura, Yukio Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex |
title | Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex |
title_full | Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex |
title_fullStr | Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex |
title_full_unstemmed | Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex |
title_short | Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex |
title_sort | somatosensation evoked by cortical surface stimulation of the human primary somatosensory cortex |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769168/ https://www.ncbi.nlm.nih.gov/pubmed/31607854 http://dx.doi.org/10.3389/fnins.2019.01019 |
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