Cargando…

Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex

Electrical stimulation of the primary somatosensory cortex using intracranial electrodes is crucial for the evocation of artificial somatosensations, typically tactile sensations associated with specific regions of the body, in brain-machine interface (BMI) applications. The qualitative characterist...

Descripción completa

Detalles Bibliográficos
Autores principales: Kirin, St. Clair, Yanagisawa, Takufumi, Oshino, Satoru, Edakawa, Kohtaroh, Tanaka, Masataka, Kishima, Haruhiko, Nishimura, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769168/
https://www.ncbi.nlm.nih.gov/pubmed/31607854
http://dx.doi.org/10.3389/fnins.2019.01019
_version_ 1783455192630427648
author Kirin, St. Clair
Yanagisawa, Takufumi
Oshino, Satoru
Edakawa, Kohtaroh
Tanaka, Masataka
Kishima, Haruhiko
Nishimura, Yukio
author_facet Kirin, St. Clair
Yanagisawa, Takufumi
Oshino, Satoru
Edakawa, Kohtaroh
Tanaka, Masataka
Kishima, Haruhiko
Nishimura, Yukio
author_sort Kirin, St. Clair
collection PubMed
description Electrical stimulation of the primary somatosensory cortex using intracranial electrodes is crucial for the evocation of artificial somatosensations, typically tactile sensations associated with specific regions of the body, in brain-machine interface (BMI) applications. The qualitative characteristics of these artificially evoked somatosensations has been well documented. As of yet, however, the quantitative aspects of these evoked somatosensations, that is to say the quantitative relationship between intensity of electrical stimulation and perceived intensity of the resultant somatosensation remains obscure. This study aimed to explore this quantitative relationship by surface electrical stimulation of the primary somatosensory cortex in two human participants undergoing electrocorticographic monitoring prior to surgical treatment of intractable epilepsy. Electrocorticogram electrodes on the primary somatosensory cortical surface were stimulated with varying current intensities, and a visual analogue scale was employed to provide a quantitative measure of intensity of the evoked sensations. Evoked sensations included those of the thumb, tongue, and hand. A clear linear relationship between current intensity and perceived intensity of sensation was observed. These findings provide novel insight into the quantitative nature of primary somatosensory cortex electrical stimulation-evoked sensation for development of somatosensory neuroprosthetics for clinical use.
format Online
Article
Text
id pubmed-6769168
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-67691682019-10-11 Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex Kirin, St. Clair Yanagisawa, Takufumi Oshino, Satoru Edakawa, Kohtaroh Tanaka, Masataka Kishima, Haruhiko Nishimura, Yukio Front Neurosci Neuroscience Electrical stimulation of the primary somatosensory cortex using intracranial electrodes is crucial for the evocation of artificial somatosensations, typically tactile sensations associated with specific regions of the body, in brain-machine interface (BMI) applications. The qualitative characteristics of these artificially evoked somatosensations has been well documented. As of yet, however, the quantitative aspects of these evoked somatosensations, that is to say the quantitative relationship between intensity of electrical stimulation and perceived intensity of the resultant somatosensation remains obscure. This study aimed to explore this quantitative relationship by surface electrical stimulation of the primary somatosensory cortex in two human participants undergoing electrocorticographic monitoring prior to surgical treatment of intractable epilepsy. Electrocorticogram electrodes on the primary somatosensory cortical surface were stimulated with varying current intensities, and a visual analogue scale was employed to provide a quantitative measure of intensity of the evoked sensations. Evoked sensations included those of the thumb, tongue, and hand. A clear linear relationship between current intensity and perceived intensity of sensation was observed. These findings provide novel insight into the quantitative nature of primary somatosensory cortex electrical stimulation-evoked sensation for development of somatosensory neuroprosthetics for clinical use. Frontiers Media S.A. 2019-09-24 /pmc/articles/PMC6769168/ /pubmed/31607854 http://dx.doi.org/10.3389/fnins.2019.01019 Text en Copyright © 2019 Kirin, Yanagisawa, Oshino, Edakawa, Tanaka, Kishima and Nishimura. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Kirin, St. Clair
Yanagisawa, Takufumi
Oshino, Satoru
Edakawa, Kohtaroh
Tanaka, Masataka
Kishima, Haruhiko
Nishimura, Yukio
Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex
title Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex
title_full Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex
title_fullStr Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex
title_full_unstemmed Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex
title_short Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex
title_sort somatosensation evoked by cortical surface stimulation of the human primary somatosensory cortex
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769168/
https://www.ncbi.nlm.nih.gov/pubmed/31607854
http://dx.doi.org/10.3389/fnins.2019.01019
work_keys_str_mv AT kirinstclair somatosensationevokedbycorticalsurfacestimulationofthehumanprimarysomatosensorycortex
AT yanagisawatakufumi somatosensationevokedbycorticalsurfacestimulationofthehumanprimarysomatosensorycortex
AT oshinosatoru somatosensationevokedbycorticalsurfacestimulationofthehumanprimarysomatosensorycortex
AT edakawakohtaroh somatosensationevokedbycorticalsurfacestimulationofthehumanprimarysomatosensorycortex
AT tanakamasataka somatosensationevokedbycorticalsurfacestimulationofthehumanprimarysomatosensorycortex
AT kishimaharuhiko somatosensationevokedbycorticalsurfacestimulationofthehumanprimarysomatosensorycortex
AT nishimurayukio somatosensationevokedbycorticalsurfacestimulationofthehumanprimarysomatosensorycortex