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Chromosome Translocations as a Driver of Diversification in Mole Voles Ellobius (Rodentia, Mammalia)
The involvement of chromosome changes in the initial steps of speciation is controversial. Here we examine diversification trends within the mole voles Ellobius, a group of subterranean rodents. The first description of their chromosome variability was published almost 40 years ago. Studying the G-b...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769443/ https://www.ncbi.nlm.nih.gov/pubmed/31510061 http://dx.doi.org/10.3390/ijms20184466 |
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author | Romanenko, Svetlana A. Lyapunova, Elena A. Saidov, Abdusattor S. O’Brien, Patricia C.M. Serdyukova, Natalia A. Ferguson-Smith, Malcolm A. Graphodatsky, Alexander S. Bakloushinskaya, Irina |
author_facet | Romanenko, Svetlana A. Lyapunova, Elena A. Saidov, Abdusattor S. O’Brien, Patricia C.M. Serdyukova, Natalia A. Ferguson-Smith, Malcolm A. Graphodatsky, Alexander S. Bakloushinskaya, Irina |
author_sort | Romanenko, Svetlana A. |
collection | PubMed |
description | The involvement of chromosome changes in the initial steps of speciation is controversial. Here we examine diversification trends within the mole voles Ellobius, a group of subterranean rodents. The first description of their chromosome variability was published almost 40 years ago. Studying the G-band structure of chromosomes in numerous individuals revealed subsequent homologous, step-by-step, Robertsonian translocations, which changed diploid numbers from 54 to 30. Here we used a molecular cytogenetic strategy which demonstrates that chromosomal translocations are not always homologous; consequently, karyotypes with the same diploid number can carry different combinations of metacentrics. We further showed that at least three chromosomal forms with 2n = 34 and distinct metacentrics inhabit the Pamir-Alay mountains. Each of these forms independently hybridized with E. tancrei, 2n = 54, forming separate hybrid zones. The chromosomal variations correlate slightly with geographic barriers. Additionally, we confirmed that the emergence of partial or monobrachial homology appeared to be a strong barrier for hybridization in nature, in contradistinction to experiments which we reported earlier. We discuss the possibility of whole arm reciprocal translocations for mole voles. Our findings suggest that chromosomal translocations lead to diversification and speciation. |
format | Online Article Text |
id | pubmed-6769443 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-67694432019-10-30 Chromosome Translocations as a Driver of Diversification in Mole Voles Ellobius (Rodentia, Mammalia) Romanenko, Svetlana A. Lyapunova, Elena A. Saidov, Abdusattor S. O’Brien, Patricia C.M. Serdyukova, Natalia A. Ferguson-Smith, Malcolm A. Graphodatsky, Alexander S. Bakloushinskaya, Irina Int J Mol Sci Article The involvement of chromosome changes in the initial steps of speciation is controversial. Here we examine diversification trends within the mole voles Ellobius, a group of subterranean rodents. The first description of their chromosome variability was published almost 40 years ago. Studying the G-band structure of chromosomes in numerous individuals revealed subsequent homologous, step-by-step, Robertsonian translocations, which changed diploid numbers from 54 to 30. Here we used a molecular cytogenetic strategy which demonstrates that chromosomal translocations are not always homologous; consequently, karyotypes with the same diploid number can carry different combinations of metacentrics. We further showed that at least three chromosomal forms with 2n = 34 and distinct metacentrics inhabit the Pamir-Alay mountains. Each of these forms independently hybridized with E. tancrei, 2n = 54, forming separate hybrid zones. The chromosomal variations correlate slightly with geographic barriers. Additionally, we confirmed that the emergence of partial or monobrachial homology appeared to be a strong barrier for hybridization in nature, in contradistinction to experiments which we reported earlier. We discuss the possibility of whole arm reciprocal translocations for mole voles. Our findings suggest that chromosomal translocations lead to diversification and speciation. MDPI 2019-09-10 /pmc/articles/PMC6769443/ /pubmed/31510061 http://dx.doi.org/10.3390/ijms20184466 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Romanenko, Svetlana A. Lyapunova, Elena A. Saidov, Abdusattor S. O’Brien, Patricia C.M. Serdyukova, Natalia A. Ferguson-Smith, Malcolm A. Graphodatsky, Alexander S. Bakloushinskaya, Irina Chromosome Translocations as a Driver of Diversification in Mole Voles Ellobius (Rodentia, Mammalia) |
title | Chromosome Translocations as a Driver of Diversification in Mole Voles Ellobius (Rodentia, Mammalia) |
title_full | Chromosome Translocations as a Driver of Diversification in Mole Voles Ellobius (Rodentia, Mammalia) |
title_fullStr | Chromosome Translocations as a Driver of Diversification in Mole Voles Ellobius (Rodentia, Mammalia) |
title_full_unstemmed | Chromosome Translocations as a Driver of Diversification in Mole Voles Ellobius (Rodentia, Mammalia) |
title_short | Chromosome Translocations as a Driver of Diversification in Mole Voles Ellobius (Rodentia, Mammalia) |
title_sort | chromosome translocations as a driver of diversification in mole voles ellobius (rodentia, mammalia) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769443/ https://www.ncbi.nlm.nih.gov/pubmed/31510061 http://dx.doi.org/10.3390/ijms20184466 |
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