Inhibition of Tyrosine-Phosphorylated STAT3 in Human Breast and Lung Cancer Cells by Manuka Honey is Mediated by Selective Antagonism of the IL-6 Receptor

Aberrantly high levels of tyrosine-phosphorylated signal transducer and activator of transcription 3 (p-STAT3) are found constitutively in ~50% of human lung and breast cancers, acting as an oncogenic transcription factor. We previously demonstrated that Manuka honey (MH) inhibits p-STAT3 in breast...

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Detalles Bibliográficos
Autores principales: Aryappalli, Priyanka, Shabbiri, Khadija, Masad, Razan J., Al-Marri, Roadha H., Haneefa, Shoja M., Mohamed, Yassir A., Arafat, Kholoud, Attoub, Samir, Cabral-Marques, Otavio, Ramadi, Khalil B., Fernandez-Cabezudo, Maria J., al-Ramadi, Basel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769459/
https://www.ncbi.nlm.nih.gov/pubmed/31491838
http://dx.doi.org/10.3390/ijms20184340

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