Increased Non-Homologous End Joining Makes DNA-PK a Promising Target for Therapeutic Intervention in Uveal Melanoma

Uveal melanoma (UM) is the most common primary intraocular tumour in adults, with a mean survival of six months following metastasis. The survival rates have not improved in over 30 years. This study has shown that sister chromatid exchange (SCE) is low in UM which is likely due to a reduced express...

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Detalles Bibliográficos
Autores principales: Doherty, Rachel E., Bryant, Helen E., Valluru, Manoj K., Rennie, Ian G., Sisley, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769470/
https://www.ncbi.nlm.nih.gov/pubmed/31480356
http://dx.doi.org/10.3390/cancers11091278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769470/
https://www.ncbi.nlm.nih.gov/pubmed/31480356
http://dx.doi.org/10.3390/cancers11091278

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