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BRAF Mutations and the Utility of RAF and MEK Inhibitors in Primary Brain Tumors
BRAF mutations have been identified as targetable, oncogenic mutations in many cancers. Given the paucity of treatments for primary brain tumors and the poor prognosis associated with high-grade gliomas, BRAF mutations in glioma are of considerable interest. In this review, we present the spectrum o...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769482/ https://www.ncbi.nlm.nih.gov/pubmed/31466300 http://dx.doi.org/10.3390/cancers11091262 |