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Epigenetic Regulation of p21(cip1/waf1) in Human Cancer
p21(cip1/waf1) is a central regulator of cell cycle control and survival. While mutations are rare, it is commonly dysregulated in several human cancers due to epigenetic mechanisms influencing its transcriptional control. These mechanisms include promoter hypermethylation as well as additional path...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769618/ https://www.ncbi.nlm.nih.gov/pubmed/31514410 http://dx.doi.org/10.3390/cancers11091343 |