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Epigenetic Regulation of p21(cip1/waf1) in Human Cancer

p21(cip1/waf1) is a central regulator of cell cycle control and survival. While mutations are rare, it is commonly dysregulated in several human cancers due to epigenetic mechanisms influencing its transcriptional control. These mechanisms include promoter hypermethylation as well as additional path...

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Detalles Bibliográficos
Autores principales: Ocker, Matthias, Al Bitar, Samar, Monteiro, Ana Carolina, Gali-Muhtasib, Hala, Schneider-Stock, Regine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769618/
https://www.ncbi.nlm.nih.gov/pubmed/31514410
http://dx.doi.org/10.3390/cancers11091343