Cargando…

The Therapeutic Effect of Curcumin in Quinolinic Acid-Induced Neurotoxicity in Rats is Associated with BDNF, ERK1/2, Nrf2, and Antioxidant Enzymes

In the present study we investigated the participation of brain-derived neurotropic factor (BDNF) on the activation of the mitogen activated protein kinase (MAPK) protein extracellular signal-regulated kinase-1/2 (ERK1/2) as a mechanism of curcumin (CUR) to provide an antioxidant defense system medi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Santana-Martínez, Ricardo A., Silva-Islas, Carlos A., Fernández-Orihuela, Yessica Y., Barrera-Oviedo, Diana, Pedraza-Chaverri, José, Hernández-Pando, Rogelio, Maldonado, Perla D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769626/ https://www.ncbi.nlm.nih.gov/pubmed/31514267 http://dx.doi.org/10.3390/antiox8090388

Ejemplares similares

Diallyl Trisulfide Protects Rat Brain Tissue against the Damage Induced by Ischemia-Reperfusion through the Nrf2 Pathway
por: Silva-Islas, Carlos A., et al.
Publicado: (2019)

Nrf2 and Redox Status in Prediabetic and Diabetic Patients
por: Jiménez-Osorio, Angélica S., et al.
Publicado: (2014)

Quinolinic Acid: An Endogenous Neurotoxin with Multiple Targets
por: Lugo-Huitrón, Rafael, et al.
Publicado: (2013)

Regulation of BDNF transcription by Nrf2 and MeCP2 ameliorates MPTP-induced neurotoxicity
por: Cao, Qianqian, et al.
Publicado: (2022)

S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo
por: Pedraza-Chaverrí, José, et al.
Publicado: (2004)

Curcumin Pretreatment Induces Nrf2 and an Antioxidant Response and Prevents Hemin-Induced Toxicity in Primary Cultures of Cerebellar Granule Neurons of Rats
por: González-Reyes, Susana, et al.
Publicado: (2013)

Peroxynitrite decomposition catalyst ameliorates renal damage and protein nitration in cisplatin-induced nephrotoxicity in rats
por: Chirino, Yolanda I, et al.
Publicado: (2004)

Effect of Curcumin in Experimental Pulmonary Tuberculosis: Antimycobacterial Activity in the Lungs and Anti-Inflammatory Effect in the Brain
por: Lara-Espinosa, Jacqueline V., et al.
Publicado: (2022)

Curcumin Pretreatment Prevents Potassium Dichromate-Induced Hepatotoxicity, Oxidative Stress, Decreased Respiratory Complex I Activity, and Membrane Permeability Transition Pore Opening
por: García-Niño, Wylly Ramsés, et al.
Publicado: (2013)

Time course study of oxidative and nitrosative stress and antioxidant enzymes in K(2)Cr(2)O(7)-induced nephrotoxicity
por: Pedraza-Chaverrí, José, et al.
Publicado: (2005)

Curcumin Attenuates Gentamicin-Induced Kidney Mitochondrial Alterations: Possible Role of a Mitochondrial Biogenesis Mechanism
por: Negrette-Guzmán, Mario, et al.
Publicado: (2015)

Dexmedetomidine attenuates the neurotoxicity of propofol toward primary hippocampal neurons in vitro via Erk1/2/CREB/BDNF signaling pathways
por: Tu, Youbing, et al.
Publicado: (2019)

Hypothyroidism attenuates protein tyrosine nitration, oxidative stress and renal damage induced by ischemia and reperfusion: effect unrelated to antioxidant enzymes activities
por: Tenorio-Velázquez, Verónica M, et al.
Publicado: (2005)

Nrf2 Activation in Chronic Kidney Disease: Promises and Pitfalls
por: Aranda-Rivera, Ana Karina, et al.
Publicado: (2022)

Genetic Variations on Redox Control in Cardiometabolic Diseases: The Role of Nrf2
por: Zazueta, Cecilia, et al.
Publicado: (2022)

Ginsenoside Rb1 attenuates methamphetamine (METH)-induced neurotoxicity through the NR2B/ERK/CREB/BDNF signalings in vitro and in vivo models
por: Yang, Genmeng, et al.
Publicado: (2022)

Curcumin Induces Nrf2 Nuclear Translocation and Prevents Glomerular Hypertension, Hyperfiltration, Oxidant Stress, and the Decrease in Antioxidant Enzymes in 5/6 Nephrectomized Rats
por: Tapia, Edilia, et al.
Publicado: (2012)

Curcumin Improves Amyloid β-Peptide (1-42) Induced Spatial Memory Deficits through BDNF-ERK Signaling Pathway
por: Zhang, Lu, et al.
Publicado: (2015)

Curcumin attenuates neurotoxicity induced by fluoride: An in vivo evidence
por: Sharma, Chhavi, et al.
Publicado: (2014)

Renoprotective effect of the antioxidant curcumin: Recent findings()
por: Trujillo, Joyce, et al.
Publicado: (2013)

S-allyl Cysteine, a Garlic Compound, Produces an Antidepressant-Like Effect and Exhibits Antioxidant Properties in Mice
por: Ruiz-Sánchez, Elizabeth, et al.
Publicado: (2020)

Nrf2 Regulation by Curcumin: Molecular Aspects for Therapeutic Prospects
por: Shahcheraghi, Seyed Hossein, et al.
Publicado: (2021)

Nrf2-Related Therapeutic Effects of Curcumin in Different Disorders
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2022)

Exercise Does Not Protect against MPTP-Induced Neurotoxicity in BDNF Happloinsufficent Mice
por: Gerecke, Kim M., et al.
Publicado: (2012)

Curcumin Attenuated Neurotoxicity in Sporadic Animal Model of Alzheimer’s Disease
por: ELBini-Dhouib, Ines, et al.
Publicado: (2021)

Overview of Nrf2 as Therapeutic Target in Epilepsy
por: Carmona-Aparicio, Liliana, et al.
Publicado: (2015)

Activation of BDNF by transcription factor Nrf2 contributes to antidepressant-like actions in rodents
por: Yao, Wei, et al.
Publicado: (2021)

A single neurotoxic dose of MDMA decreases BDNF expression in the frontoparietal cortex but not in the hippocampus
por: Vas, Szilvia, et al.
Publicado: (2009)

Anti-Viral Potential and Modulation of Nrf2 by Curcumin: Pharmacological Implications
por: Rahban, Mahdie, et al.
Publicado: (2020)

Curcumin reverses erastin-induced chondrocyte ferroptosis by upregulating Nrf2
por: Zhou, Yizhao, et al.
Publicado: (2023)

Curcumin Promotes A-beta Fibrillation and Reduces Neurotoxicity in Transgenic Drosophila
por: Caesar, Ina, et al.
Publicado: (2012)

Curcumin attenuates copper-induced oxidative stress and neurotoxicity in Drosophila melanogaster
por: Abolaji, Amos O., et al.
Publicado: (2020)

Therapeutic Effect of Curcumin on 5/6Nx Hypertriglyceridemia: Association with the Improvement of Renal Mitochondrial β-Oxidation and Lipid Metabolism in Kidney and Liver
por: Ceja-Galicia, Zeltzin Alejandra, et al.
Publicado: (2022)

Potential Effects of Nrf2 in Exercise Intervention of Neurotoxicity Caused by Methamphetamine Oxidative Stress
por: Chen, Lin, et al.
Publicado: (2022)

CSF neopterin and quinolinic acid are biomarkers of neuroinflammation and neurotoxicity in FIRES and other infection‐triggered encephalopathy syndromes
por: Dale, Russell C., et al.
Publicado: (2023)

BDNF-TrkB/proBDNF-p75(NTR) pathway regulation by lipid emulsion rescues bupivacaine-induced central neurotoxicity in rats
por: Jia, Danting, et al.
Publicado: (2023)

The MLN4924 inhibitor exerts a neuroprotective effect against oxidative stress injury via Nrf2 protein accumulation
por: Andérica-Romero, Ana Cristina, et al.
Publicado: (2016)

Curcumin and Nano-Curcumin Mitigate Copper Neurotoxicity by Modulating Oxidative Stress, Inflammation, and Akt/GSK-3β Signaling
por: Sarawi, Wedad S., et al.
Publicado: (2021)

Dexmedetomidine Attenuates Methotrexate-Induced Neurotoxicity and Memory Deficits in Rats through Improving Hippocampal Neurogenesis: The Role of miR-15a/ROCK-1/ERK1/2/CREB/BDNF Pathway Modulation
por: Taha, Mohamed, et al.
Publicado: (2023)

Neuroprotection by Curcumin in Ischemic Brain Injury Involves the Akt/Nrf2 Pathway
por: Wu, Jingxian, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_784cdekj9lpqsuc6lk5svr8sm1