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Targeting Autophagy for Overcoming Resistance to Anti-EGFR Treatments

Epidermal growth factor receptor (EGFR) plays critical roles in cell proliferation, tumorigenesis, and anti-cancer drug resistance. Overexpression and somatic mutations of EGFR result in enhanced cancer cell survival. Therefore, EGFR can be a target for the development of anti-cancer therapy. Patien...

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Detalles Bibliográficos
Autores principales: Kwon, Yoojung, Kim, Misun, Jung, Hyun Suk, Kim, Youngmi, Jeoung, Dooil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769649/
https://www.ncbi.nlm.nih.gov/pubmed/31527477
http://dx.doi.org/10.3390/cancers11091374