Cargando…

Targeting Autophagy for Overcoming Resistance to Anti-EGFR Treatments

Epidermal growth factor receptor (EGFR) plays critical roles in cell proliferation, tumorigenesis, and anti-cancer drug resistance. Overexpression and somatic mutations of EGFR result in enhanced cancer cell survival. Therefore, EGFR can be a target for the development of anti-cancer therapy. Patien...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kwon, Yoojung, Kim, Misun, Jung, Hyun Suk, Kim, Youngmi, Jeoung, Dooil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769649/ https://www.ncbi.nlm.nih.gov/pubmed/31527477 http://dx.doi.org/10.3390/cancers11091374

Ejemplares similares

Role of HDAC3-miRNA-CAGE Network in Anti-Cancer Drug-Resistance
por: Kwon, Yoojung, et al.
Publicado: (2018)

FcεRI-HDAC3-MCP1 Signaling Axis Promotes Passive Anaphylaxis Mediated by Cellular Interactions
por: Kim, Misun, et al.
Publicado: (2019)

Exosomal MicroRNAs as Mediators of Cellular Interactions Between Cancer Cells and Macrophages
por: Kwon, Yoojung, et al.
Publicado: (2020)

Homoharringtonine Inhibits Allergic Inflammations by Regulating NF-κB-miR-183-5p-BTG1 Axis
por: Kim, Misun, et al.
Publicado: (2020)

EGR3-HDAC6-IL-27 Axis Mediates Allergic Inflammation and Is Necessary for Tumorigenic Potential of Cancer Cells Enhanced by Allergic Inflammation-Promoted Cellular Interactions
por: Kwon, Yoojung, et al.
Publicado: (2021)

Histone Deacetylase Inhibitors to Overcome Resistance to Targeted and Immuno Therapy in Metastatic Melanoma
por: Yeon, Minjeong, et al.
Publicado: (2020)

MiR-154-5p-MCP1 Axis Regulates Allergic Inflammation by Mediating Cellular Interactions
por: Kim, Misun, et al.
Publicado: (2021)

Targeting HDAC6 to Overcome Autophagy-Promoted Anti-Cancer Drug Resistance
por: Jo, Hyein, et al.
Publicado: (2022)

Human Adipose Tissue-Derived Mesenchymal Stem Cells Attenuate Atopic Dermatitis by Regulating the Expression of MIP-2, miR-122a-SOCS1 Axis, and Th1/Th2 Responses
por: Kim, Misun, et al.
Publicado: (2018)

HDAC6 and CXCL13 Mediate Atopic Dermatitis by Regulating Cellular Interactions and Expression Levels of miR-9 and SIRT1
por: Kwon, Yoojung, et al.
Publicado: (2021)

Histone Deacetylase-3/CAGE Axis Targets EGFR Signaling and Regulates the Response to Anti-Cancer Drugs
por: Kim, Hyuna, et al.
Publicado: (2016)

MiR-135-5p-p62 Axis Regulates Autophagic Flux, Tumorigenic Potential, and Cellular Interactions Mediated by Extracellular Vesicles During Allergic Inflammation
por: Kim, Misun, et al.
Publicado: (2019)

CAGE Binds to Beclin1, Regulates Autophagic Flux and CAGE-Derived Peptide Confers Sensitivity to Anti-cancer Drugs in Non-small Cell Lung Cancer Cells
por: Yeon, Minjeong, et al.
Publicado: (2018)

Tubulin Beta3 Serves as a Target of HDAC3 and Mediates Resistance to Microtubule-Targeting Drugs
por: Kim, Youngmi, et al.
Publicado: (2015)

DDX53 Promotes Cancer Stem Cell-Like Properties and Autophagy
por: Kim, Hyuna, et al.
Publicado: (2017)

The CAGE–MiR-181b-5p–S1PR1 Axis Regulates Anticancer Drug Resistance and Autophagy in Gastric Cancer Cells
por: Yeon, Minjeong, et al.
Publicado: (2021)

miR-335 Targets SIAH2 and Confers Sensitivity to Anti-Cancer Drugs by Increasing the Expression of HDAC3
por: Kim, Youngmi, et al.
Publicado: (2015)

HDAC2 as a target for developing anti-cancer drugs
por: Jo, Hyein, et al.
Publicado: (2023)

miR-30a Regulates the Expression of CAGE and p53 and Regulates the Response to Anti-Cancer Drugs
por: Park, Deokbum, et al.
Publicado: (2016)

Roles of RNA Methylations in Cancer Progression, Autophagy, and Anticancer Drug Resistance
por: Jo, Hyein, et al.
Publicado: (2023)

miR-217 and CAGE form feedback loop and regulates the response to anti-cancer drugs through EGFR and HER2
por: Kim, Youngmi, et al.
Publicado: (2016)

DDX53 Regulates Cancer Stem Cell-Like Properties by Binding to SOX-2
por: Kim, Youngmi, et al.
Publicado: (2017)

CAGE-miR-140-5p-Wnt1 Axis Regulates Autophagic Flux, Tumorigenic Potential of Mouse Colon Cancer Cells and Cellular Interactions Mediated by Exosomes
por: Yeon, Minjeong, et al.
Publicado: (2019)

Potential of the miR-200 Family as a Target for Developing Anti-Cancer Therapeutics
por: Jo, Hyein, et al.
Publicado: (2022)

Nuclear localization signal domain of HDAC3 is necessary and sufficient for the expression regulation of MDR1
por: Park, Hyunmi, et al.
Publicado: (2014)

Advances in targeting EGFR allosteric site as anti-NSCLC therapy to overcome the drug resistance
por: Maity, Swastika, et al.
Publicado: (2020)

HDAC3 acts as a negative regulator of angiogenesis
por: Park, Deokbum, et al.
Publicado: (2014)

The Hyaluronic Acid–HDAC3–miRNA Network in Allergic Inflammation
por: Kim, Youngmi, et al.
Publicado: (2015)

TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway
por: Oh, Se Jin, et al.
Publicado: (2023)

Targeting autophagy to overcome drug resistance: further developments
por: Chang, Haocai, et al.
Publicado: (2020)

The Potential of Senescence as a Target for Developing Anticancer Therapy
por: Jo, Hyein, et al.
Publicado: (2023)

Cancer/Testis Antigens as Targets for RNA-Based Anticancer Therapy
por: Shim, Kyeonghee, et al.
Publicado: (2023)

miR-122-SOCS1-JAK2 axis regulates allergic inflammation and allergic inflammation-promoted cellular interactions
por: Noh, Kyeonga, et al.
Publicado: (2017)

Combined Inhibitions of Glycolysis and AKT/autophagy Can Overcome Resistance to EGFR-targeted Therapy of Lung Cancer
por: Ye, Mingtong, et al.
Publicado: (2017)

The pentapeptide Gly-Thr-Gly-Lys-Thr confers sensitivity to anti-cancer drugs by inhibition of CAGE binding to GSK3β and decreasing the expression of cyclinD1
por: Kim, Youngmi, et al.
Publicado: (2017)

Targeting Autophagy to Overcome Human Diseases
por: Condello, Maria, et al.
Publicado: (2019)

AUY922 Effectively Overcomes MET- and AXL-Mediated Resistance to EGFR-TKI in Lung Cancer Cells
por: Choi, Yun Jung, et al.
Publicado: (2015)

Novel agents and strategies for overcoming EGFR TKIs resistance
por: Niu, Fei-Yu, et al.
Publicado: (2014)

Emerging strategies to overcome resistance to third-generation EGFR inhibitors
por: Shi, Kunyu, et al.
Publicado: (2022)

Identification of Targetable Liabilities in the Dynamic Metabolic Profile of EGFR-Mutant Lung Adenocarcinoma: Thinking beyond Genomics for Overcoming EGFR TKI Resistance
por: Gkountakos, Anastasios, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_d8vpdtnnkr3pl1kq6on6n4p3ol