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Fumaric Acids Do Not Directly Influence Gene Expression of Neuroprotective Factors in Highly Purified Rodent Astrocytes

(1) Background: Dimethylfumarate (DMF) has been approved for the treatment of relapsing remitting multiple sclerosis. However, the mode of action of DMF and its assumed active primary metabolite monomethylfumarate (MMF) is still not fully understood. Former reports suggest a neuroprotective effect o...

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Detalles Bibliográficos
Autores principales: Pars, Kaweh, Gingele, Marina, Kronenberg, Jessica, Prajeeth, Chittappen K, Skripuletz, Thomas, Pul, Refik, Jacobs, Roland, Gudi, Viktoria, Stangel, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769695/
https://www.ncbi.nlm.nih.gov/pubmed/31546798
http://dx.doi.org/10.3390/brainsci9090241